Blockbuster Scale Single-Use Platform: for bulk drug substance up to 300l in only one fully disposable unit.
Science - Temperature comparison full load vs. part load
Part load with 1x RoSS®,
7.6l filling volume
Part load with 9x RoSS® and different filling volumes from 2,3l to 7,6l
Part load with 20x RoSS® each 7,6l filling volume
The freezing curves and kinetics are very similar and independent of the RoSS® shells loading (min. or full load) as long the individual RoSS® Shells are identically with same set up (bag size and filling volume).
That’s one of the advantages and differentiators of the RoSS® shell due to the design and combination of polyethylene sidewalls and stainless steel on top and bottom this can be achieved.