The One Process for Large Volumes in Biopharma

The single-use technologies based on RoSS® are a combination of integrated platform systems, sterile consumables and auxiliary services to achieve process excellence in commercial GMPhandling of up to 500L of bulk drug substances or more per batch.

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Why is this process the one for you?

  • The Flexible One

    Independent from type, manufacturer and size of your single-use bag, the modular platforms and single-use technologies will meet your requirements.

  • The Trusted One

    With more than 300.000 RoSS shells sold and 400 platform systems commissioned, Single Use Support is a trusted pioneer in biopharma for optimizing drug substance handling. 

  • The Secure One

    Automated aseptic filling at highest accuracy minimizes both operational human errors and overfilling of single-use bags. Controlled plate-based freezing and thawing of single-use bags prevents loss of product quality due to cryoconcentration and reproducible freezing and thawing.

  • The Simple One

    Ease of use paired with small footprint: single-use platform systems from Single Use Support are easy to install, user friendly to operate and does not require a predefined infrastructure on-site.
Preview of Single Use Support's ebook about filling gaps in managing large volumes of biologics

Download eBook

eBook: Filling gaps in managing large scale volume of biologics

This eBook gives you more insights about:

  • What gaps need to be filled in bioprocessing?
  • Hurdles to overcome in handling pharmaceuticals
  • New approaches to tackle these challenges
  • Future Prospects: A glimpse into the crystal ball
eBook: Filling gaps in managing large scale volume of biologics
 

Robust storage & shipping

  • RoSS technologies provide process flexibility for smallest volumes with highest accuracy:

    • Closed, robust and tamper-evident protection of your single-use bag for highly valuable drug substances
    • Vendor-agnostic and hence compatible to other systems during senstive freezing applications
    • Process flexibility for safe handling regardless of type and size of bag manufacturer without being trapped in siloed biopharma process solutions 
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  • Diagram of the fluid management process of bulk drug substances with labeld steps on a transparent background.

Fluid management & cold chain handling for bottles

  • Single Use Support offers its integrated and vendor-independent fill-filtration & freeze-thaw platforms also for usage with single-use PE bottles. Contact us for more information.

  • Five-step process diagram for drug substance handling in single-use bottles with icons and labels for filling, protecting, freezing, storing, and shipping.

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Downloads

Preview of Single Use Support's solution overview about bulk drug substances
Solution overview: Bulk drug substances
Preview of Single Use Support's solution overview about bulk drug substances
Solution overview: Bulk drug substances
 
Preview of an app note about filling and freezing of RNA therapeutics
App Note: The Chilled Future of RNA Therapeutics Filling & Freezing Applications
Preview of an app note about filling and freezing of RNA therapeutics
App Note: The Chilled Future of RNA Therapeutics Filling & Freezing Applications
 
Preview of Single Use Support's case study about scalable freezing and thawing
Study: Scalable freezing & thawing of pharmaceutical bulk drug substance
Preview of Single Use Support's case study about scalable freezing and thawing
Study: Scalable freezing & thawing of pharmaceutical bulk drug substance
 

More information

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Bulk drug substance management

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Microbial and bacterial fermentation is of great importance in the production of biologics, especially for the manufacturing of small molecules. The filling and freezing of large volumes for fermentation is an essential part during different produ...

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