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Blast freeze-thaw system | RoSS.BLST

Blast freeze-thaw system | RoSS.BLST

RoSS.BLST is a GMP-compatible system for blast freezing & thawing of drug substances. It is suitable for any primary packaging from all manufacturers and allows freezing and thawing within a temperature range of -80°C to +40°C.

The modular and mobile internal rack system offers maximal flexibility and enables a simple transfer from blast freezing to ultra-cold storage.

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Capacity for up to 300L
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Available to Lease
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Down to -80°C

Features and benefits of RoSS.BLST

  • Blast freezing and thawing down to -80°C and up to +40°C
  • Suitable for any primary packaging from all manufacturers
  • Mobile and customizable internal rack system or drawer solution
  • GMP-compatible, automated, at highest possible speed and accuracy
  • Optional shaking function for optimized thawing time
  • Seamless transition from freezing to ultra-cold storage
  • Selected configurations are offered as pre-defined, process-ready designs to reduce lead time.

What are the main benefits of controlled blast freezing?

  • Biomanufacturing operator handling frozen bioprocess containers, wearing protective gear in front of controlled blast freezer.

  • Controlled freezing is essential for sensitive biologics to ensure uniform temperature distribution. Even minor variations in temperature can affect protein stability, potency, and overall product quality.

    Controlled blast freezers offer the advantage of applying defined and optimized freezing rates, which reduce the risk of cryoconcentration and preserve molecular integrity. Additionally, they enable reproducible and scalable processes, ensuring consistent results across batches and supporting GMP readiness.

    Next-generation blast freezers, such as the RoSS.BLST, further improve upon this technology with advanced airflow control and flexible, adjustable cooling profiles.

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Downloads

Preview of RoSS.BLST datasheet
RoSS.BLST - Datasheet
Preview of RoSS.BLST datasheet
RoSS.BLST - Datasheet
 
Preview whitepaper controlled blast freezing of bulk-packaged DS - Single Use Support
Controlled blast freezing for bulk-packaged drug substance - Whitepaper
Preview whitepaper controlled blast freezing of bulk-packaged DS - Single Use Support
Controlled blast freezing for bulk-packaged drug substance - Whitepaper
 

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