Biopharma­ceuticals handling at a higher level to grow their safety. quality. efficiency. flexibility. margin.

Bag supplier agnostic: Applicable for all established single-use bag manufacturers in the market. Scalable, Flexible & Ultra-Safe.

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Supporting single-use systems in biopharma, the Austrian industrial process solution provider revolutionizes the management of drug substances at sub-zero temperatures.

Closing gaps between Downstream and Fill & Finish Single Use Support offers to an innovative and 100% secure logistics process ensuring “better support for the pharma industry”.


Striving for scalable solutions? Solutions that are integrated into a fully end-to-end solution process? Irrespective of the type of single use bag used? And not worrying about product loss?

Single Use Support owns the expertise to fully support your requirements.


Cutting-edge technologies from Single Use Support are applicable anytime when liquid biopharmaceuticals are being frozen and transported – ranging from small volumes in clinical studies for ADCs, viral vectors, mAbs up to commercial large volumes of bulk drug substance.


Learn Single Use Support’s portfolio of technologies covering all process steps of end-to-end solutions, comprising of protecting single use bags during transportation, filling into primary packaging, freeze and thaw units for controlled freezing and many auxiliary equipment to top off professional management of drug substance handling.

Most recent articles


Find here the most recent news articles, press releases and product news from Single Use Support.

Johannes Kirchmair_Thomas Wurm

Single Use Support achieves 260% year-on-year revenue growth to over EUR 130 million

RFID Digitalization of single-use systems

At the forefront of Pharma 4.0

BioPhorum Logo

Single Use Support joins BioPhorum

Safety & Speed: handling two major factors in CAR T-cell therapy

Safety & Speed: handling two major factors in CAR T-cell therapy

Logistic solutions for CAR T-cell therapy - let's scale!

Logistic solutions for CAR T-cell therapy – let’s scale!

Small batch manufacturing & fill-finish in cell and gene therapy

Small batch manufacturing & fill-finish in cell and gene therapy

Supply chain optimization in cell and gene therapies

Supply chain optimization in cell and gene therapies

Advanced therapy medicinal products - a new era of medicine

Advanced therapy medicinal products – a new era of medicine


MyManifold: Quick configuration of single-use manifold assemblies

Cell and gene therapy: In vivo and Ex vivo in comparison

Cell and gene therapy: In vivo and Ex vivo in comparison


Single Use Support – innovation for biopharma logistics made in Tyrol

Single Use Support was founded in 2015 by Johannes Kirchmair and Thomas Wurm. It was and is their aim to improve the logistics process for liquids in the biopharma industry on the basis of “Single Use Bags”. All too often the two founders of Single Use Support were confronted with great losses of highest-quality biopharma liquids caused by leakages or bio contamination.

The reason are tiniest material deficiencies of Single Use Bags that are not tested, as well as faulty packaging, and mostly frozen bags that are scarcely protected from external mechanical influences. Furthermore, substantial variations in temperature in the cold chain pose a logistical problem that regularly causes the loss of highest-quality biopharma intermediates or end products.

From off-the-shelf single use bags to next level development

Single Use Support’s first solution is RoSS® – a specifically developed shell system that nestles the relatively sensitive “Single Use Bag” – primarily in case of frozen applications. Single Use Support offer their RoSS® system for all established manufacturers and filling quantities, like Sartorius or ThermoFisher single-use bags. Instead of cardboard or polystyrene they use a composite of high quality foam and stainless steel. But RoSS®, with all its obvious protective advantages, was only the beginning.

When sealed, the fairly sensitive single use bag turns into a highly stable shell system, which facilitates the storage of liquids in the tightest of spaces.The individual RoSS® containers can be placed in the RoSS.SHIP developed by Single Use Support in a compact way. The stable RoSS® Shell units are stored in the stainless steel container construction RoSS.SHIP consuming the equivalent space/volume of standard shipping goods (footprint of a Euro palette). Compact and safe, the liquids contained in the single-use bags and stored in the RoSS.SHIP containers can be consistently cooled in the isolated RoSS.SHIP container, both actively and passively. For single-use end-to-end processes, the RoSS.SHIP container is also available in different materials.

Single-use bags – those are the issues

The issue of undetected material deficiencies was not yet solved. Single Use Support took the challenge to present the biopharma industry with solutions for preventing risks. With their MITS.2D, Single Use Support have developed a mobile integrity test system that enables the testing of a single-use bag with a capacity of up to 50 liters in less than a minute in order to guarantee its 100% functionality and tightness. Thus, the MITS is the first integrity test that can be used on the spot in order to assure the intactness of the “single-use bag”.

BULK.STREAM – the newly developed logistics process for liquids

For Single Use Support, the missing link in the process thus far was the systematic filling of the single-use bags, which in practice is a manual and comprehensive process. This has changed with the development of RoSS.FILL. The Rack (tailored to the single-use bags in use as well as the respective RoSS Shell) is fitted with the RoSS® units that are attached to the filling hoses. Up to 20 RoSS® Shells can be filled per rack with an accuracy of +-10mL. Fully automated, 200 liters are aliquot in less than an hour and with a safety degree of 100%.

  • Use of single-use bags of all established manufacturers (ThermoFisher, Sartorius, Cytiva, Meissner, PALL, Merck/Millipore, Entegris)
  • RoSS®, RoSS.SHIP, RoSS.FILL are available for all established filling quantities and single-use bag sizes
  • Compatibility with all established connecting systems
  • Drastically increased warehousing and shipping safety
  • Significantly increased warehousing capacity thanks to the low product volume of RoSS® Shell
  • Superior shipping safety (air, freight, loading process)
  • Cooling, tracking and scalable shipping volume (transparency & controlling)
  • A completely closed process chain with the BULK.STREAM®being the robust bridge from downstream all the way to fill & finish

The logistics process for biopharma liquids is underdeveloped

The entire process, which has been reconsidered and newly developed by Single Use Support, was named BULK.STREAM® by the company’s founders – it stands for “moving liquids in bulk”, like bulk drug substances (BDS), all the way from the downstream to the fill & finish process.

“It is our aim to increase the patient safety and to fashion core processes more intelligently than in the past”, as Single Use Support founders Kirchmair and Wurm state. “Considering the value of the substances, not only for the pharma industry but also for the patients, the established logistics process solutions for biopharma liquids are absolutely underdeveloped.”