Ultra-low Temperature Storage Freezer | RoSS.ULTF

RoSS.ULTF is an upright ultra-low temperature storage freezer for frozen drug substances in different sizes. The fridge for laboratories keeps the desired set point temperature down to -80°C/-112°F. 

Our ULT storage freezer is compatible with RoSS Shells to protect your bioprocess containers. It offers highest storage density, is fully movable and can be modularly adapted to your individual needs.

Product Photo_RoSS.ULTF_transparent
temperature-control

Down to -80°C / -112°F

capacity

Capacity for up to 300L

scalable (1)

Modular Interior

Advantages of the high density ultra-low temperature storage freezer

  • Great relief for ultra-cold room storage capacities due to its high storage density and stackability of RoSS shells
  • Seamless transitions between deep-freezing (RoSS.pFTU) and shipping (RoSS.SHIP) or thawing in an end-to-end process
  • High degree of flexibility in-plant due to its portable use
  • strong helping hand in-plant to prevent staff from carrying heavy loads manually
  • Another way out from incompatibilities of technologies due to its tailored design

Facts on the ULT storage freezer RoSS.ULTF

  • Insulated container for long-term cooling of drug substances in RoSS Shells
  • Upright freezer style
  • Ultra-low temperature storage freezer: Holds desired temperature down to -80°C/-112°F
  • Ease of use for loading: place loaded Trolleys or Racks as a whole inside
  • Fully modular and customized interior
  • GMP compliant alarm management
  • Temperature monitoring
  • Flexible storage location
  • Compatibility to RoSS single-use technologies
  • Contains up to 300L of drug substance
  • Powered by natural gases
  • Choose between water- or air-cooled system
Ultra cold storage freezer - RoSS.ULTF high density

As a modular and efficient Ultra-Low Temperature (ULT) storage freezer, it is the perfect solution for all requirements. It outperforms both, conventional upright laboratory freezers and walk-in freezers and cold rooms thanks to its advantages for all biomanufacturing companies; full temperature control thanks to reliable air temperature conformity and a highly modular interior that can be equipped with shelving systems to store all available single-use bags and bottles.

Simply place pallets into RoSS.ULTF - without changing the regulation-intensive infrastructures. Thus RoSS.ULTF enables modular and easy-to-install cold room storage capacity that smartly fills a gap for the biopharmaceutical industry between small-scale low storage density lab freezers and large but expensive and fixed walk-in freezers.

RoSS.ULTF_Comparison_Missing Link_Puzzle

Advantages of RoSS.ULTF to other solutions in the industry

 

Conventional Lab Freezer

RoSS.ULTF Ultra-low temperatur Storage Freezer

Walk-in Freezer & Cold Room

Comments

Temperature control

×

Reliable air temperature uniformity of ±3°C and wide-ranging setpoints with RoSS.ULTF

Storage density

Pallets, racks and other packaging to be stored efficiently

Modularity

Customized shelving systems for sizes of primary packaging

Cost effectiveness

Simple installation and maintenance of ULT storage freezers 

Backup plan

Digital alarm infrastructure and long preservation of temperature in case of failure

Our customers trust in us:

Rentschler Biopharma SE

Lonza

SCHOTT Pharma

Freezer for labs meets all requirements

The ultra-low temperature storage freezer RoSS.ULTF is designed to meet the requirements of a fridge or freezer for labs: the storage freezer allows highest temperature stability down to -80°C/-112°F, and is compatible with RoSS Shells to provide maximum protection for single-use bags.

In addition to its high flexibility, this lab storage freezer comes with great storage space, easy access and is stackable; also, RoSS.ULTF is scalable and therefore suitable to deliver enough space both as a fridge or freezer for labs and in bulk production and storage of biopharmaceuticals.

Manual defrost is not necessary to keep the freezer storage within the RoSS.ULTF frost-free, and with the temperature alarm, stainless steel surfaces, adjustable temperature down to -80°C/-112°F and precise temperature control, this device delivers freezer space that is ready to meet both lab requirements and international regulations.


 

RoSS.ULTF_Modularity_Single Use Support

Integrate into your cold chain process

As part of the Freeze & Thaw platform by Single Use Support, RoSS.ULTF is a device ready to be integrated in highly delicate cold chains. This platform allows seamless transitions from the unfrozen to the frozen and back to the unfrozen state of biologics: Together with the RoSS.pFTU – a powerful freeze/thaw unit that comes in different sizes –, it enriches Single Use Support’s Portfolio of professional end-to-end solutions.

In order to provide even more efficiency, safety and user-friendliness within the freeze/thaw process, Single Use Support additionally provides various consumables, such as RoSS Shell. The product is designed to protect single-use bioprocess containers during storage and transport and is compatible with the Freeze & Thaw platfrom RoSS.pFTU.

Data sheet

Datasheet_RoSS.ULTF

Datasheet RoSS.ULTF

Filesize: 0.54 MB – Mime-Type: application/pdf

Whitepaper RoSS.ULTF_Maintaining ultra low temperatures

Whitepaper: RoSS.ULTF Cold Chain at Ultra-Low Temperatures

Filesize: 1.58 MB – Mime-Type: application/pdf

Case Study_RoSS.ULTF_Universal Ultra Cold Storage

Case Study - Universal Ultra Cold Storage

Filesize: 1.34 MB – Mime-Type: application/pdf

More solutions

Product Photos_RoSS.pFTU Lab Scale_transparent_webpage

RoSS.pFTU Lab-Scale | Plate Freeze & Thaw

1mL-10L: Laboratory freezer, compatible with single use bags of all sizes and manufacturers. Our lab freezer is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process.

Down to -80°C / -112°F
Up to 10L
Controlled rate freezing & thawing
Product Photos_RoSS.pFTU MidScale_transparent_webpage

RoSS.pFTU Mid-Scale | Plate Freeze & Thaw

Up to 100L: Our mid scale freezer is a plate freezer and thaw unit designed for RoSS shells, to protect your preferred single-use bag during cryogenic applications. 

RoSS.pFTU mid scale is compatible with single-use bioprocess containers of all sizes and manufacturers and shows best product stability results for your biopharmaceuticals up to 100L. 

Down to -80°C / -112°F
Up to 100L
Controlled rate freezing & thawing
Product Photos_RoSS.pFTU Large Scale_transparent_webpage

RoSS.pFTU Large-Scale | Plate Freeze & Thaw

Up to 400L: Our large scale freezing platform system is a plate-based pharmaceutical freeze and thaw unit. The system enables controlled rate freezing and is compatible with single-use bags of all sizes and manufacturers.

Down to -80°C / -112°F
Up to 400L
Controlled rate freezing & thawing
ross-shak-shaker

ROSS.SHAK | Shaker

RoSS.SHAK is your reliable shaker to regain highest quality and homogeneity of your biopharmaceuticals.

RoSS.SHAK enables constant shaking of your protein to regain homogeneity and product quality after freezing. Shakes up to 70L per run in 3 pre-defined speeds.

Product homogeneity
Up to 100L per run
Up to 20L bags
RoSS.PADL_Rendering_Single Use Support

RoSS.PADL | Homogenizing Solution

RoSS.PADL is a scalable massaging platform for achieving a uniform mixture in
single-use bags. With integrated cooling and heating, it maintains optimal temperatures
consistently.

Bag Independent
Consistent Homogeneity
Temperature Control
Product Photos_RoSS.LN2F_transparent_webpage

RoSS.LN2F | Cryogenic Freezer

RoSS.LN2F is a powerful cryogenic controlled rate freezer for temperatures down to -170°C/-274°F. An enclosed LN2 system and our innovative direct injection system ensure no direct exposure and no mechanical compressors are needed. This ensures a safe, low-maintenance and energy-saving handling.

Down to -170°C / -274°F
Increased Cell Viability
Down to < 250mL/ Bag

FAQ about ultra-low temperature storage

What are ultra-low temperature freezers used for?

Ultra-low temperature freezers are designed to achieve extremely low temperatures, required for example for a safe storage of many biologics. Frequently used in single use technologies.

What products can be stored and shipped with a laboratory freezer?

There is a wide range of products that can be stored and shipped in single-use bags within a laboratory fridge or freezer. The RoSS.ULTF is compatible with RoSS Shells, made to protect these very bags and to facilitate a seamless transition between the freezing/thawing and storage processes. Products stored and shipped this way include drug substances, monoclonal antibodies, mRNA and gene therapies, temperatures as low as -75°C.

However, there are certain products that need to be stored at even lower temperatures, such as cell therapies or gene-modified cell therapies: This is where cryogenic freezers come into place, with the RoSS.LN2F able to reach temperatures down to -180°C.

Who uses the ultra-cold freezer RoSS.ULTF?

The ultra-cold freezer RoSS.ULTF is used all along the biopharma industry, from laboratories to transport experts and in biopharma companies. Since it offers high storage density and is easily stackable, it is extremely flexible in use and can be integrated in processes from lab to bulk scale.

What is the difference between a household freezer and an ultra-cold temperature freezer?

In contrast to the usual household chest freezers or upright freezers with wire baskets that can be found at various retailers including Amazon next to whirlpools and other rather ordinary household products, ultra-cold temperature freezers are highly specialized devices far more powerful than fridge-freezers or the extra-freezer on casters. They can reach temperatures that household devices – even the bestselling, best chest freezers – cannot achieve with cold air from an ordinary compressor.

Although ULT freezers might share some typical functions with small chest freezers (like a power-on indicator light that helps to become aware of power outage), ultra low temperature freezers need not only to provide lower, but also more stable temperatures than a compact chest freezer, since it contains far more delicate substances.

What characterizes an ultra-cold temperature freezer?

Typically, ultra-cold temperature freezers can achieve temperatures as low as -80 °C, which sets them apart from mini fridges, upright freezers /deep freezers that are used for food storage like ice cream in households or ice makers for a large family. While interior light via LED light, door alarm, the size of the single storage baskets, free delivery and warranty may be the decisive factors when buying a household device, ultra-cold storage freezers need to provide not only extremely low temperatures, but also the highest accuracy and cost-effectiveness. Storage density (how many cu ft / cubic feet of cold storage) is also a key factor in the considerations on which ultra-cold storage freezer to choose.

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Single-use technologies, which reduce the risk of cross-contamination of high-quality bulk drug substances, are becoming increasingly popular in the pharmaceutical industry. You can find out the reason for this in the blog post!
 

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