Advanced Fluid & Cold Chain Management for Large Volumes

The One Process for Large Volumes in Biopharma

The single-use technologies based on RoSS® are a combination of integrated platform systems, sterile consumables and auxiliary services to achieve process excellence in commercial GMP handling of up to 500L of bulk drug substances or more per batch.


Why is this process the one for you?

The Flexible One

Independent from type, manufacturer and size of your single-use bag, the modular platform single-use technologies will meet your requirements.

The Secure One

Automated aseptic filling at highest accuracy minimizes both operational human errors and overfilling of single-use bags. Controlled plate-based freezing and thawing of single-use bags prevents loss of product quality due to cryoconcentration and reproducible freezing and thawing.

The Trusted One

With more than 200.000 RoSS shells sold and 180 platform systems commissioned within the last 3 years, Single Use Support is a trusted pioneer in Biopharma for optimizing drug substance handling. 

The Simple One

Ease of use paired with small footprint: single-use platform systems from Single Use Support are easy to install, user friendly to operate and does not require a predefined infrastructure on-site.

Learn more

eBook_Filling Gaps in Managing Large Volume of Biologics_Single Use Support

eBook: Filling Gaps in Managing Large Volumes of Biologics

Filesize: 3.99 MB – Mime-Type: application/pdf


Bulk.Stream RoSS shell

RoSS® Shell | Protecting single-use bags

The RoSS® Shell is the safest solution for Robust Storage and Shipping of biopharmaceuticals. Protecting all available single-use bags in different scales to reduce product loss to < 0.001%.

IRIS Single-Use Assmeblies_Production Kufstein-29

IRIS Manifold | Single-Use Assemblies

As an expert in single-use solutions, we have made it our goal to deliver vendor agnostic single-use assemblies manufactured at highest quality standards in ISO 7 cleanrooms and sterilized within shortest lead times. Prevent downtime and ensure an uninterrupted supply chain in compliance with GMP and regulatory requirements with our single-use manifold assemblies using silicone tubing and connectors of your choice.


RoSS.FILL Base | Fill-Filtration

Automated aseptic aliquotation of bulk drug substance into single-use bioprocess containers at highest accuracy and throughput speed. Different scales and sizes of up to 480L in 2D single-use biocontainers to be filled thanks to modular platform design.

RoSS.PFTU XL_Large Volume Freeze-Thaw_Single Use Support

RoSS.pFTU XL | Plate Freeze & Thaw | 500L per Batch

Controlled freezing and thawing of thousand of liters in biopharmaceutical  manufacturing processes. Automated plate-based freeze-thaw unit for 500 liters per batch of any liquid substances including vaccines, media, buffer solutions or other drug substances.

RoSS.LODR open loading single-use shell

RoSS.LODR | Foldable gripper arm

RoSS.LODR is a mobile and foldable gripper arm that ensures ergonomic handling during loading or unloading activities. RoSS.LODR supports a safe working environment and can significantly reduce work related repetitive strain injuries.


RoSS.FRDG | Ultra Cold Storage Freezer

Reliable ultra-cold storage down to -80°C (-112°F) with best-in-class temperature conformity, high storage capacity and modular interior design.


RoSS.SHIP | Ship, Track & Trace

RoSS.SHIP secures the cold chain shipping and storing of bulk drug substance for almost one week. Highly robust, stackable, coolable and compact – Fort Knox for high-quality substances!

Robust Frozen Storage & Shipping

RoSS Technologies provide process flexibility for large volumes at highest quality.

  • Closed, robust and tamper-evident protection of your single-use bag for highly valuable drug substances
  • Vendor-agnostic and hence compatible to other systems during senstive freezing applications
  • Process flexibility for safe handling regardless of type and size of bag manufacturer without being trapped in siloed biopharma process solutions 
e2e-stream-bulk drug substances

Fluid Management & Cold Chain Handling for Bottles

Single Use Support offers its integrated and vendor-independent fill-filtration & freeze-thaw platforms also for usage with single-use PE bottles. Contact us for more information.

Enabling end-to-end process solutions for bottles

Consult one of our experts

More information

Solution Overview_Bulk Drug Substances_Single Use Support

Solution Overview for Bulk Drug Substances

Filesize: 2.45 MB – Mime-Type: application/pdf

Whitepaper: Scalable Freezing & Thawing of Pharmaceutical Bulk

Whitepaper: Scalable Freezing & Thawing of Pharmaceutical Bulk

Filesize: 1.13 MB – Mime-Type: application/pdf

App Note_RNA Therapeutics Filling Freezing Applications

App Note: The Chilled Future of RNA Therapeutics Filling & Freezing Applications

Filesize: 0.84 MB – Mime-Type: application/pdf