News

June 23, 2022

CAR T manufacturing process and the supply chain behind it

micheal-eder
Michael Eder

Mastering the complex CAR T manufacturing process and the associated supply chain challenges in the cell and gene area are the major bottlenecks during the large-scale commercialization of highly promising CAR T cell products. 


 

June 9, 2022

mRNA vaccines: How to safely ship and store them

daniel-tischler
Daniel Tischler

mRNA vaccines require high diligency along their supply chain. This is why every step in the mRNA vaccine supply chain must be carefully planned, carried out in a safe and controlled manner and requires appropriate, innovative technologies.

June 9, 2022

Gene therapy manufacturing - 5 requirements to scale up

michael-muehlegger
Michael Mühlegger

Gene therapies have become a highly promising field of groundbreaking next generation treatment, but there are some challenges to face within the manufacturing process. Here are 5 factors that will be crucial for upscaling gene therapy manufacturing with single-use technology.

May 18, 2022

Plate freezing: best approach for freezing biopharmaceuticals

daniel-tischler
Daniel Tischler

Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation, with several advantages for biopharma.

May 18, 2022

Autologous vs allogeneic cell therapy

barbara-m-fischer
Barbara M. Fischer

Although autologous and allogeneic cell therapies share both defining methodological key elements as well as various fields of application, including most innovative cancer therapies, there are significant differences between them. Therefore, a closer look on both procedures shall be presented.

May 18, 2022

Industry 4.0 in Biomanufacturing: RoSS.KSET as an example

michael-muehlegger
Michael Mühlegger

Industry 4.0 has long become reality in many branches. In Pharma 4.0 intelligent industrial applications and IoT enable players in the bioeconomy industry  to transition to operations that help them improve their productivity. Pharma 4.0 also has become a major part in single-use technologies, as it brings companies to the next level concerning the scalability, productivity and efficiency of their processes and products. 

April 14, 2022

Extractables vs. leachables: definitions, differences & facts

lorenzo-de-benedictis
Lorenzo De Benedictis

Extractables and leachables are contaminants that are causing biopharmaceutical manufacturers headaches, as they can lead to impurities of highly valuable drug products. While extractables and leachables both describe foreign matter that can lead to contamination of highly valuable drug products, it is important to understand their characterization but also the difference between the two.

April 14, 2022

Case Study: The relief through customized manifolds

micheal-eder
Michael Eder

In order to comply with the versatile requirements of today’s market, flexibility and the option to customize are key whilst maintaining availability and short lead times. This is true for many areas, not least when it comes to the ever-growing number of single-use technologies utilized in the biopharmaceutical industry, be it for research and development or small- and large scale production.

April 13, 2022

Single-use design made simple with our configurator

lorenzo-de-benedictis
Lorenzo De Benedictis

Flexibility and the option to customize are key for any company wanting to make it in today’s highly competitive and highly regulated market. Learn more!

April 13, 2022

Manufacturer independent single-use assemblies

lorenzo-de-benedictis
Lorenzo De Benedictis

Our manifold configurator gives customers the freedom to design their fully customized aseptic tubing assemblies quickly and easily with just a few clicks, thus allowing them to achieve greater flexibility and independence. You ask how? It is pretty simple - read on!