GENE-MODIFIED CELL THERAPY

Close-up of a pipette dispensing blue liquid into a multi-well plate in a laboratory setting.

Gene-Modified Cell Therapy Manufacturing Solutions

Gene-modified Cell Therapies enable unique approaches to novel treatments. After collection of cells from patients the genes are edited ex vivo to boost their function and persistence before they are re-administered into the patients body. This includes CAR-T (chimeric antigen receptor) therapies.

The manufacturing process for gene-modified cell therapies comes along with challenges during fluid and cold chain management. It is of utmost importance to rely on safe cold chain solutions and handling processes for both drug products and vector products.

Fluid Management Solutions around Single-Use Technologies for Gene-Modified Cell Therapies

Discover Single Use Support's range of solutions for reliable cold chain management, automated drug substance dispensing and filling and logistical handling for cell therapy and vector product developers and manufacturers.

Freezing and thawing at controlled freezing rate is essential to achieve minimized cell damage and maintained cell viability after thawing gene-modified cell therapies. Furthermore, automated liquid transfer, aliquotation, storage and shipment solutions facilitates safe and standardized handling of personalized therapies at different scales and accelerate turnaround times until readminstration.

Preview of Single Use Support's application note about controlled filling and freezing of cells

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App Note: "Bestcellers": Controlled Filling & Freezing of Cells

Explore how modular, GMP-compliant technologies streamline the sterile filling and cryopreservation of cells for therapies, banking, and culture. This application note highlights how Single Use Support’s solutions enable precise aliquotation, scalable freezing down to -150°C, and high post-thaw viability - reducing product loss and manual inefficiencies in cell-based manufacturing.

App Note: "Bestcellers": Controlled Filling & Freezing of Cells
 

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