Cell Banking

CELL BANKING

Close-up image of a RoSS.KSET with a frozen single-use bag inside.

Cold Chain Solutions in Cell Banking

In the process of creating new drug compounds cells play an important role. However, handling of cells, i.e., cell banking requires very careful and fast processes in order to guarantee best-possible quality.

When cryopreserving cells it is crucial to achieve a high cell recovery rate and ultimately optimal cell viability after thawing. Controlled cGMP-compliant and scalable freezing enables reproducible processes and thus standardization. Study results confirm a consistent and uniform high ratio of live cell recovery after cryopreservation of cells in single-use bioprocess containers thanks to plate-based RoSS.pFTU Lab Scale leading to accelerated cell-based process workflow.

Solutions for Optimized Cryopreservation of Cells

State-of-the-art single-use technologies improve fluid management and cold chain management of cell significantly. Elaborated solutions accelerate the process of aliquoting and freezing cells to less than 1 hour whilst providing full control over accuracy during automated aseptic dispensing and controlled cryogenic freezing with liquid nitrogen down to -170°C.

Graphic showing simple aliquoting and freezing process for cell banking applications in less than 1 hour.

Cell Banking for Seed Train Intensification

Cell Banking is a crucial step in the seed train intensification process for biopharmaceutical production. To get the train rolling, multiple optimized process units, that enable high cell densities cultivation & efficient high cell density cryopreservation, need to be combined.

Preview of Single Use Support's guide about seed train intensification

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Guide: Banking the Intensified Seed Train

High-density cell banking is a crucial step in the seed train intensification process for biopharmaceutical production. To get the train rolling, multiple optimized process units, that enable high cell densities cultivation & efficient high cell density cryopreservation, need to be combined.Download our free Whitepaper and learn more.

Guide: Banking the Intensified Seed Train

"Bestcellers": Controlled Filling & Freezing of Cells

Sterile aliquoting into single-use bags and freezing for cryopreservation of cells pose challenges for laboratories and manufacturers. Download the App Note to learn more about the implications and approaches to address these challenges.

Preview of Single Use Support's application note about controlled filling and freezing of cells

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App Note: "Bestcellers": Controlled Filling & Freezing of Cells

Explore how modular, GMP-compliant technologies streamline the sterile filling and cryopreservation of cells for therapies, banking, and culture. This application note highlights how Single Use Support’s solutions enable precise aliquotation, scalable freezing down to -150°C, and high post-thaw viability - reducing product loss and manual inefficiencies in cell-based manufacturing.