Articles written by Khalil Essani
Interview: Trends with Single-Use Bottles in Bioprocessing
One could read a lot about single-use bags in biopharmaceutical industry as a primary packaging in bioprocessing in the previous last years. The rise of bags has become more relevant, since they largely replaced single-use bottles. Nevertheless, s...
Fluid management in biopharma: Advantages of single-use systems
Fluid management in biopharma has changed considerably in recent years. With the advances in life science and the related healthcare adaptations, the manufacturing and supply chain divisions of biopharmaceutical companies are going through a major...
Upstream intensification from lab to mAb manufacturing
Upstream process intensification is something you currently hear a lot in the context of upstream bioprocessing (USP) optimization. One of the upstream intensification processes being addressed is seed train intensification. This is the use of ...
Stressing Cells: The Role of Cryoprotectants in ATMP Cryopreservation
In cell and tissue therapies, living cells are used to treat previously chronic diseases, like cancer forms, arthritis, or certain autoimmune disorders. To be effective, the living therapeutic product requires administration with a sufficient c...
Seed train intensification - the next big step in biopharma?
Seed train intensification is an approach in upstream bioprocessing that is gaining more and more attention. With the growing demand for new drugs, manufacturers have to ensure both efficient and flexible production processes. While generally a...
DMSO: Freezing Cells
What is DMSO? DMSO, or dimethyl sulfoxide, is a colorless liquid that is used for cell preservation. Thanks to its unique properties, it has found its way into laboratories worldwide. DMSO plays a vital role in protecting cells when temperatures d...
Protein production and optimization strategies
Protein production is a fundamental process in biotechnology, enabling the creation of essential molecules for medical, industrial, and research purposes. As demands for diagnostic and therapeutic proteins continue to rise, the implementation o...
Protein stability – all you need to know
The stability of proteins determines their ability to maintain their functional conformation under different environmental conditions, such as changes in temperature, pH, and solvent composition. It is an important aspect in pharmaceutical manu...
Interview: Efficient Cell Banking in Seed Train Intensification
Khalil Essani, Product Line Manager at Single Use Support, is an expert in bioprocessing applications for single-use technologies. He provides valuable insights, advantages and solutions using cell banking in seed train intensification in the f...