Freeze-Thaw platform

The Single Use Support freeze-thaw platforms provide reliable end-to-end solutions for the controlled freeze/thaw processes of any drug substance - either for clinical phases or commercialized bulk production. 

Our new freeze-thaw units are fully scalable and compatible with all batch sizes and bags from all established manufacturers – you will only require one single system from the lab to blockbuster production.


Fast lead times


Worldwide shipping


Personal customer service



RoSS.pFTU Lab-Scale | 1mL-5L

Compatible with single use bags of all sizes and manufacturers. Our lab scale freezer is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process.


RoSS.pFTU Mid-Scale | Up to 70L

Our mid scale freezer is a plate-based Freeze/Thaw unit designed for RoSS shells, to protect your preferred single-use bag during cryogenic applications. 

RoSS.pFTU mid scale is compatible with single-use bioprocess containers of all sizes and manufacturers and shows best product stability results for your biopharmaceuticals up to 70L. 

RoSS PFTU_Large Scale_Freeze-Thaw Platform

RoSS.pFTU Large-Scale | Up to 220L

Our large scale freezing platform system is a plate-based freeze-thaw unit for any scale and batch size. Well-established RoSS.pFTU large scale is compatible with single-use bags of all sizes and manufacturers. The hybrid solution offers freeze-thaw capabilities for bags and bottles up to 220L in one platform.  


RoSS.FRDG | Ultra Cold Storage

RoSS.FRDG is a storage fridge for frozen drug substances in different sizes. It keeps the desired set point temperature down to -80°C. RoSS.FRDG is compatible with RoSS Shells, stackable itself, fully moveable and shippable. 


ROSS.SHAK | Shaker

RoSS.SHAK is your reliable shaker to regain highest quality and homogeneity of your biopharmaceuticals.

RoSS.SHAK enables constant shaking of your protein to regain homogeneity and product quality after freezing. Shakes up to 70L per run in 3 pre-defined speeds.


RoSS.PADL | Homogenizing

RoSS.PADL is a scalable platform for cooling your single-use bag whilst gently massaging it to ensure there is a homogenous mixture of the solution. With the RoSS.PADL multiple cooling and massaging mechanisms can be placed side by side with one control system.

Our customers trust in us:

3SBio Inc.

The combination of a bag agnostic robust secondary packaging (RoSS®) and the scalable plate based freeze/thaw technologies convinced us to select Single Use Support. It not only matches all our requirements, it is also safe, easy to navigate and flexible to single use bags from any supplier.


Thanks to a fortunate coincidence, we got in touch with Single Use Support. Not only have we found a more than solid single-use solution for our main problem thanks to their product RoSS®, but we now have access to a clever and 100% safe drug substance logistics system.


Having partners such as Single Use Support in place will be one of many essential components as we scale our operations to deliver high-quality programs and vector production services to our clients.


Whats makes the Freeze-Thaw platform so special?

Fully automated

Fully-automated freeze & thaw process, at highest possible speed and accuracy. CFR Part 11 and GMP-compliance as a further milestone for the biopharma manufacturers. Freeze/thaw recipe for lab scale also transferable for large scale.


Compatible with single use bags of all established manufacturers, sizes and capacities. Hybrid version to freeze & thaw vials, bottles and single use bags in one platform possible. Or upgrade to LN2 freezing down to -180°C.

Unrestricted Scalability

The scalable solutions for freezing and thawing ranges from the RoSS.pFTU lab scale to RoSS.pFTU large scale. For CGT or cell culture inoculation using either multiple small bags or up to one 5L bag, there is RoSS.pFTU lab scale. Your way up to blockbuster commercial production is possible with RoSS.pFTU large scale. From 10mL up to 50L bags and a batch size of up to 200L and more you can scale-up or down as required.


Safe and controlled freezing of high-value biopharmaceuticals will be pushed to a higher level: Tamper-evident closed system with optimal freezing kinetcs leading proven product stability and freezing process with best results for mABs, BDS, CGT, ADCs, viral vectors or any other vaccines.


Blast vs. Plate based Freeze/Thaw units

We tried to visualize Cryoconcentration by using Naphthol Blue Black as color agent. An in- tense blue coloration shows a high concentration of dissolved solutions. The bags frozen in the plate freezer exhibit a homogenous tinge with a white line running through the center. The bag frozen in the static freezer exhibits higher concentration levels in the lower areas.

blast freezer "slow freezing"

Dark blue spots indicate a higher cryoconcentration


plate freezer “fast freezing”

A homogeneous freezing, no dark blue spots are visible.


More solutions


RoSS.FILL | Fill-Filtration

RoSS.FILL is a fully automated single-use bag filling & filtration system. This allows maximum flexibility and scalability of both the filling and draining process. It is possible to fill unlimited volumes per batch with a speed of up to 300 liters per hour. The entire filling process is fully disposable, thus warranting an absolutely sterile fill & drain process. For further productivity improvements check out our pinch valve innovation.


MITS.2D | Integrity Testing System

Everything else is like “hoping that all goes well.”
With a patented system, MITS.2D tests single use bags with a capacity of up to 20 liters in less than 60 seconds to make sure they are 100% intact.


RoSS® Shell | Protecting single-use bags

Reduce product loss with the safest transport solution for all available single-use bioprocess containers. Robust. Scalable. Single-use bag independent.

More information


Whitepaper: How controlled freezing enables scalability

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.


An overview of relevant suppliers: Freeze Thaw in Biopharma

In order to preserve biopharmaceutical properties, bulk drug substances are commonly frozen before they are being stored or sent on their way around the globe. Read more about the players and their innovations!


Pharmaceutical freezer: How to meet requirements for safe storage and shipping?

In biopharma and similar industries there is a lot of talk about the freezing process! In this article you learn everything about the freezing process of drug substances in the biopharma industry. Find out why SUSupport can help you!


Lab freezer for single use technology

The elimination of cost-intensive, bulky installations saves a considerable amount of budget during construction. Single use technology, especially the single use bags are very easy and cost-saving to store. Read here what else speaks for the bags!


Freeze-thaw platform revolutionizing the drug substance logistics process

With bulk drug substances playing an increasingly important role in the pharmaceutical and biopharmaceutical industry, the need for a reliable freeze/thaw process as well as safe shipping and storage is more important than ever.


Thawing antibodies - Freeze Thaw technology for handling mAbs on a higher quality level

In a field as sensitive as biopharmaceutical development and production, controlled processes and procedures have always played a vital role and will continue to do so. Learn more why Single-use technologies are highly flexible, scalable and on another quality level.

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