RoSS.pFTU Large-Scale Hybrid

Freeze-Thaw | Bags and Bottles

The Hybrid Freeze and Thaw Platform freezes and thaws larger volumes of drug substances in both single-use bioprocess containers and bottles. All in one: plate-based freezing of single-use bags, protected in RoSS shells, and air flow freezing of bottles control cold chain management of valuable liquids in both primary packagings.

RoSS.pFTU large scale with its hybrid option is compatible with single-use bags and bottles from all manufacturers and of all sizes up to 400L and beyond.

RoSS PFTU_Large Scale_Freeze-Thaw Platform_Hybrid

Advantages of controlled plate-freezers

Dark blue spots indicate a higher cryoconcentration. 
Fast & controlled freezing with a plate freezer enables a homogeneous freezing result.

Advantages of controlled plate-freezers-Grafik

Description

Hybrid Freeze & Thaw platform system for freezing and thawing of larger volumes of drug substances in both, single-use bags and bottles.

  • Capacity 
    • Single-use bags: Up to 220 L and more, depending on bag type
    • Bottles: Up to 160 L and more, depending on bottle type
  • Freezing type
    • Plate-based freezing and thawing unit for single-use bags, protected in RoSS shells.
    • Freezing and thawing with air flow for bottles, protected in Bottle CCUs.
  • Usage for mid to large scale batch sizes. Scale-up for late phase studies or commercial production
  • Primary packaging independent: any bag vendor, any size. Bag or bottle.
  • Best product stability results for mABs and BDS
  • GMP-compliant, automated, at highest possible speed and accuracy
  • Freezes down to -90°C

Our customers trust in us:

Fujifilm Diosynth

Moderna

AGC Biologics

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