RoSS.PADL | Homogenizing Solution

Cool & Gentle Homogeneity

RoSS.PADL is a platform to standardize cooling/heating of your single-use bag while it is gently kneaded to ensure a homogenous mixture of your substance. 

With the RoSS.PADL platform, multiple cooling/heating and kneading mechanisms can be placed side by side to scale-up with one control system.

Product Photo_RoSS.PADL-1-trim

Fast lead times

Worldwide shipping

Personal customer service


What makes RoSS.PADL the optimal solutions?

Automate your process

Where normally an operator would massage the bag, this process can be automated to increase process efficience and reduce the risk of inconsisten product quality. The removal of human invervention means a scalable process for one or more bioprocess containers in parallel and the reduced risk of human error in bag handling.

Bag & connector agnostic

No matter the manufacturer of the bag, the RoSS.PADL Homogenizer does not differentiate and is scalable to the customer's needs.

Fluid homogeneity through kneading & cooling/heating

With RoSS.PADL it is possible to ensure homogeneity during draining of the single-use bag. The integrated cooling/heating plate thereby ensures optimum temperatures between -2°C to 30°C/ 28°F to 86°F.

Controllable with other RoSS devices

Seamless integration into end-to-end solutions from Single Use Support. Simple combination with protective RoSS Shells for single-use bags, RoSS.pFTU Freeze-Thaw Platforms and RoSS.FILL Fill-Drain Units.

RoSS.PADL Homogenizer

Cool your fluid & generate homogeneity.

RoSS.PADL is a scalable massaging platform for achieving a uniform mixture in single-use bags. The integrated cooling/heating mechanism ensures that the correct temperature is maintained. In addition, the biocontainer can be filled during the process and completely emptied due to the slope. Furthermore, multiple RoSS.PADL units can be seamlessly arranged side by side and controlled with a single unit, enhancing efficiency and productivity.

In some instances, human intervention is used to massage the bags during draining. With RoSS.PADL this is no longer necessary. With the RoSS.PADL multiple cooling and massaging mechanisms becomes automated, reproducible and therefore standardized. Bags can be placed side by side with one control system to increase process efficiency.

RoSS.PADL provides a further solution within the Single Use Support end-to-end process and is controllable with the RoSS.FILL Fill & Drain Platform.


  • Suitable for all 2D single-use bags from 500mL up to 20L
  • Standalone or controllable over RoSS.FILL HMI
  • Automated stroke depth depending on the bag used
  • Adjustable stroke frequency (30 to 60 strokes/minute)
  • Integrated cooling/heating function 
  • Optional bubble sensors available
  • Bag & connector agnostic
  • Suitable for cleanroom and GMP-compliant construction
  • Seamless integration into end-to-end solutions from Single Use Support
Product Photo_RoSS.PADL-4

Our customers trust in us:

Rentschler Biopharma SE





Datasheet RoSS.PADL

Filesize: 0.36 MB – Mime-Type: application/pdf

Whitepaper_RoSS.PADL_Ensuring Homogeneity in the Aliquoting of Biopharmaceuticals

Whitepaper: Homogeneity in Biopharmaceutical Aliquotation

Filesize: 0.95 MB – Mime-Type: application/pdf

More solutions

Lab freezer pharma with RoSS.pFTU labscale

RoSS.pFTU Lab-Scale | Freeze-Thaw

1mL-5L: Compatible with single use bags of all sizes and manufacturers. Our lab scale freezer is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process.


RoSS.FILL CGT | Fill-Filtration

Fully automated filling system used for small single use bags from 20ml to 500ml for cell & gene therapies. RoSS.FILL CGT contains 1 control unit and 1 rack with highly accurate weights.


RoSS.pFTU Mid-Scale | Plate Freeze & Thaw

Up to 100L: Our mid scale freezer is a plate freezer and thaw unit designed for RoSS shells, to protect your preferred single-use bag during cryogenic applications. 

RoSS.pFTU mid scale is compatible with single-use bioprocess containers of all sizes and manufacturers and shows best product stability results for your biopharmaceuticals up to 100L. 


RoSS.FRDG | Ultra Cold Storage Freezer

RoSS.FRDG is an ultra cold storage fridge for frozen drug substances in different sizes. The ultra cold freezer keeps the desired set point temperature down to -75°C. RoSS.FRDG offers highest storage density, is fully movable and can be modularly adapted to your individual needs.


ROSS.SHAK | Shaker

RoSS.SHAK is your reliable shaker to regain highest quality and homogeneity of your biopharmaceuticals.

RoSS.SHAK enables constant shaking of your protein to regain homogeneity and product quality after freezing. Shakes up to 70L per run in 3 pre-defined speeds.

Cryogenic Freezer RoSS LN2F

RoSS.LN2F | Cryogenic Freezer

RoSS.LN2F is a powerful cryogenic controlled rate freezer for temperatures down to -170°C/-274°F. An enclosed LN2 system and our innovative direct injection system ensure no direct exposure and no mechanical compressors are needed. This ensures a safe, low-maintenance and energy-saving handling.

More information

Simplyfication for optimizing performance efficiency with single-use technologies

Single-use end-to-end solutions - flexible, scalable and reliable

In an extremely complex, competitive and constantly evolving sector such as the biopharmaceutical industry, flexibility is key, not least since it is an immensely varied and compliance-driven field. Learn more in this article!

Scalability single-use drug substances

Scalability of single-use drug substance production

The aim was to achieve a freezing process where the last point of freeze always happens at the same time throughout all scales. If successful, the generated freezing curves will look very similar. Temperature ramps have been used to slow down or accelerate the freezing process.

Single-use bag manufacturers biopharmaceutical market Single Use Support

Single-use bag manufacturers: the major players

The advanced platforms of the newest generation of single use bags are generally compatible with a variety of bag brands and volumes. One of these platforms is Single Use Support’s RoSS®, which offers the benefit of not only being bag agnostic but also highly flexible thanks to its modular design. Learn more about the biggest player in the industry!


Homogenization of cells & aliquotation in single-use bags

Who can relate to the situation when every cell aliquot is different? That's why cell homogenization and aliquotation are important requirements in modern cell biology research, relevant for scientists and laboratory staff. Scientists and process engineers benefit from uniform cell distribution throughout multiple single-use bioprocess containers for cell banking or other bioprocessing steps.

RoSS.PADL Homogenizing Solution for Aliquot-to-Aliquot consistency

Aliquotation & homogenization of viral vectors

In this article, we uncover the significance of a professional aliquotation process, the challenges entailed in filling viral vectors like AAVs, and the innovative solutions supporting to master those challenges.

Send a Request