Homogenizing and cooling system | RoSS.PADL

RoSS.PADL is a scalable massaging and mixing system for achieving a uniform mixture in single-use bags. With integrated cooling and heating, it maintains optimal temperatures consistently. This makes it well suited for applications such as cell & gene therapies or seed train intensification, where it helps to maintain cell counts across different single-use bags. 

With the RoSS.PADL platform, multiple cooling/heating and kneading mechanisms can be placed side by side to scale-up with one control system.

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Bag Independent

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Consistent Homogeneity

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Temperature Control

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What makes RoSS.PADL the optimal homogenizing solution?

Automate your process

Where normally an operator would massage the bag, this process can be automated to increase process efficience and reduce the risk of inconsisten product quality. The removal of human invervention means a scalable process for one or more bioprocess containers in parallel and the reduced risk of human error in bag handling.

Bag & connector agnostic

No matter the manufacturer of the bag, the RoSS.PADL Homogenizer does not differentiate and is scalable to the customer's needs.

Fluid homogeneity through kneading & cooling/heating

With RoSS.PADL it is possible to ensure homogeneity during draining of the single-use bag. The integrated cooling/heating plate thereby ensures optimum temperatures between -2°C to 30°C.

Controllable with other RoSS devices

Seamless integration into end-to-end solutions from Single Use Support. Simple combination with protective RoSS Shells for single-use bags, RoSS.pFTU Freeze-Thaw Platforms and RoSS.FILL Fill-Drain Units.

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RoSS.PADL: cool your fluid & generate homogeneity

RoSS.PADL is a homogenizing platform that standardizes the cooling & heating of single-use bags while gently kneading it to ensure a homogeneous mixture of cells.  In addition, the biocontainer can be filled during the process and completely emptied due to the slope. Furthermore, multiple RoSS.PADL units can be seamlessly arranged side by side and controlled with a single unit, enhancing efficiency and productivity.

In some instances, human intervention is used to massage the bags during draining. With RoSS.PADL this is no longer necessary. With the RoSS.PADL multiple cooling and massaging mechanisms becomes automated, reproducible and therefore standardized. Bags can be placed side by side with one control system to increase process efficiency.

RoSS.PADL provides a further solution within the Single Use Support end-to-end process and is controllable with the RoSS.FILL Fill & Drain Platform.

Facts

  • Suitable for all 2D single-use bags from 500mL up to 20L
  • Standalone or controllable over RoSS.FILL HMI
  • Automated stroke depth depending on the bag used
  • Adjustable stroke frequency (30 to 60 strokes/minute)
  • Integrated cooling/heating function 
  • Optional bubble sensors available
  • Bag & connector agnostic
  • Suitable for cleanroom and GMP-compliant construction
  • Seamless integration into end-to-end solutions from Single Use Support
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Datasheets

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Datasheet RoSS.PADL

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Whitepaper: Homogeneity in Biopharmaceutical Aliquotation

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Videos

RoSS.PADL // Homogenizing Solution for Single-Use Bags

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