Ensuring High Viability CHO Cells in Seed Train Intensification

Speaker: Brian Moloney, Director Key Account Management & Khalil Essani, Product Line Manager

Seed train intensification is an upstream development approach to reduce manufacturing time, cost and contamination risk while increasing process consistency and yield. High cell density cultures or cell intermediates are aliquoted into single-use bags that help eliminate multiple expansion steps. However, the CHO cell viability is threatened by exposure to DMSO for a prolonged period at room temperature and uncontrolled freezing processes. 

Watch this webinar on demand to learn more about the process of seed train intensification, the challenges of aliquotating and cryopreserving CHO cells, and how to achieve high cell viability and recovery.

What if your supply chain for single-use equipment was robust?

The pandemic should have taught us that dual or multi-sourcing helps to strengthen supply chains. But did you know that the implications for manufacturers and CDMOs are even greater?

Watch this webinar on demand to learn more about the possibilities of using vendor-independent components for your biopharmaceutical fluid path.

Key Takeaways:

• Increasing the robustness and reliability of the biopharmaceutical fluid path.
• Saving on supplier validation costs and time.
• Analyzing how pricing regulations affect market dynamics and production efficiency.

Speaker: David Seifert, Head of Sales Application Engineering (Sterile Consumables) & Khalil Essani, Product Line Manager (Sterile Consumables)

Bag & Shell – the Setup to Step up

The Perfect Combination for Cold Chain Management

Speaker: Claus Exenberger, Product Line Management, Single Use Support and Sarah Lemon, Product Manager, MilliporeSigma

What you'll learn:

1. What helps manufacturers and CDMOs adopt an improved freeze/thaw solution
2. Background on tests performed to validate integrity, scalability, and security in freeze/thaw and cold chain shipping applications
3. Why the Mobius® 2D freeze single-use assembly and the RoSS® shell are such a good fit

Rewatch the webinar to learn more about the combination of single-use bags and protective shells and their advancements in cold chain management.

Controlled ATMP Freezing: Leap Forward in Cell Viability

Speaker: Alexander Fuchs, Senior Teamlead Product Line Management.

What you'll learn:

1. What is the optimal freezing rate to enhance cell viability post-thaw?
2. Comparison of freezing methods and its impact on a CHO cell
3. What technologies can take control over ATMP freezing?

Rewatch our webinar to learn more about controlled-rate cold chain management technologies for Advanced Therapy Medicinal Products that optimize cell viability and process efficiency in different areas of biomanufacturing.

Reinventing Aseptic Aliquoting in Biopharma

1. What do biopharma filling platforms and lasers have in common?
2. Which findings have advanced ATMP and Biopharma processes?
3. And what functionalities are really needed in the industry in regards to aliquoting liquids?

Find out all this and more about advanced fluid management technologies that drive safety & process efficiency in different areas of biomanufacturing. It touches a wide range from ATMP aliquotation, media and buffer bulk addition, seed train intensification to large volume bacterial fermentation. Speaker: Brian Moloney, Director of New Products & Innovation.

Freeze-Ship-Thaw: Hidden Champions for Biopharma & CGT Networks

Learn more about why Freeze-Ship-Thaw is an underestimated enabler to build strong Bio and CGT networks.  

1. Why is this process a catalyst for global networks?
2. What are your options? What's now and what's next?
3. How big is Cold Chain Management? Market size and outlook?
4. Vision:  How will it look like in 2030?

Watch the on-demand webinar from Johannes Kirchmair, CEO of Single Use Support.

ATMP Fluid & Cold Chain Management

Are you looking to improve your fluid and cold chain management process for ATMP manufacturing? Join us for a free webinar, to learn about controlled handling of fluids in ATMP manufacturing and how it can eliminate product loss and increase process efficiency.

Learn how to optimise fluid and cold chain management in ATMP manufacturing - A NIBRT webinar in collaboration with Single Use Support. Single Use Support's speaker is Brian Moloney.

Don't Freeze To Death. Control Freezing

How modular and yet universal freezing technologies improve product quality of your drug substances during cold chain logistics?

Listen to Roland Jenewein, CTO at Single Use Support, on demand who has talked live on March 14, 2023.

• Discover possibilities to optimize product quality with controlled plate-based freezing solutions
• Learn how far scalable freezing can go in a manufacturing environment through a case study
• Understand indications of a successful freeze/thaw cycle and cryopreservation

New era of drug substance cold chain management

Billions of dollars is what the pharma industry loses each year due to product loss based on lacking or insufficient protection of single-use bags used for liquid transfer. With over 200,000 RoSS®️ shells shipped, less than 0.001% product loss has been reported. Single Use Support has created products and technologies to address exactly these key concerns. The robust shell to protect single-use bioprocess containers in the process of freezing, storing, and shipping, RoSS® (Robust Storage and Shipping), is agnostic to manufacturer, design, and volume, allows for the safe handling of frozen and thus fragile single-use bags. Accompanying freeze and thaw as well as fill and drain systems work in synergy with the shell for single-use bags to allow for a safe solution for optimized fluid management.

Speaker: Michael Wieland