Khalil Essani - Single Use Support

Khalil Essani

Product Line Management

Khalil Essani is Product Line Manager at Single Use Support. Scientist through and through he develops single-use technologies to further advance the biopharmaceutical industry during its shift towards single-use systems. Based on his extensive expertise and graduate in bioprocessing and biotechnology Khalil authors several publications. At Single Use Support he focuses on sterile products in the field of fluid and cold chain management.

Articles written by Khalil Essani

End-to-end Solution

Protein production and optimization strategies

Protein production is a crucial process that which a large variety of pharmaceutical products rely on. Therefore, we will discuss this procedure in this article, along with possibilities to improve it.


 

Khalil Essani - Single Use Support

Khalil Essani

April 9, 2024

End-to-end Solution

Protein stability – all you need to know

Protein stability is crucial to be maintained along the manufacturing process of protein-based products. In this article, we will discover what influences protein stability, along with methods to assess and increase it.

Khalil Essani - Single Use Support

Khalil Essani

April 9, 2024

Cell Banking

Interview: Efficient Cell Banking in Seed Train Intensification

Khalil Essani, Product Line Manager at Single Use Support, is an expert in bioprocessing applications for single-use technologies. He provides valuable insights in the use of cell banking in seed train intensification.

Khalil Essani - Single Use Support

Khalil Essani

April 4, 2024

Single-use Consumables

Annex 1 and the PUPSIT requirement

Annex 1 and PUPSIT meant significant changes in the pharmaceutical sector. In this article, we will illustrate the focus areas of Annex 1 and will discuss main aspects of PUPSIT.

Khalil Essani - Single Use Support

Khalil Essani

March 13, 2024

Single-use Consumables

Overview of filter integrity testing methods

There are various approaches to validate the integrity of sterile filters, as is required by several regulatory frameworks. We will cover some of the most common methods in this article.

Khalil Essani - Single Use Support

Khalil Essani

March 13, 2024

Cell & Gene Therapy

Regulations for Cryoprotectants in ATMP Cryopreservation

Adequate quality control samples retained before cell therapy treatment are a crucial component of effective regulation and need to represent the conditions and history in the cryobag. A deep dive into GMP Annex 1 on ATMP Cryopreservation.

Khalil Essani - Single Use Support

Khalil Essani

February 7, 2024

Cell & Gene Therapy

Stressing Cells: The Role of Cryoprotectants in ATMP Cryopreservation

The objective of an optimal cryopreservation strategy is to deactivate (put on hold) degenerative cellular pathways and preserve proliferative potential by reducing the temperature below –130°C. To reduce the effects of ice crystal and osmotic injuries, cryopreservation protocols usually incorporate cryoprotective agents (CPAs).

Khalil Essani - Single Use Support

Khalil Essani

February 8, 2024

Monoclonal Antibodies

Steps in Monoclonal Antibody Production

From the selection of antigens to the utilization of bioreactors, each stage in the production journey significantly contributes to the quality, specificity, and scalability of monoclonal antibodies. With a focus on single-use technologies, we explore how innovations are shaping the future landscape of mAb production. 

Khalil Essani - Single Use Support

Khalil Essani

February 6, 2024

Monoclonal Antibodies

Trends in monoclonal antibody production: Optimizing processes with single-use technology

Several trends are re-shaping monoclonal antibody manufacturing – from the minimized use of in vivo practices to the implementation of automated processes. In this article, we will highlight 5 current trends in mAb manufacturing.

Khalil Essani - Single Use Support

Khalil Essani

January 18, 2024

Monoclonal Antibodies

Monoclonal antibody production process: a comprehensive guide

The monoclonal antibody manufacturing process is an essential cornerstone in research as well as in the production of diagnostic and therapeutic tools. Therefore, we will take a closer look at how mAbs are made – in this article.

Khalil Essani - Single Use Support

Khalil Essani

January 18, 2024

Vaccines

How single-use technologies improve vaccine production

Single-use technologies bring several advantages to vaccine production, from fluid management to cold chain measures. We will uncover the most important benefits of SUT for this sector in this article.

Khalil Essani - Single Use Support

Khalil Essani

December 7, 2023

Viral Vectors

Non-viral vectors vs. viral vectors in gene therapy

When designing gene therapies, the choice between non-viral and viral vectors plays an important role in determining the success and safety of therapeutic interventions. Non-viral vectors offer unique advantages, while viral vectors have their own set of strengths and weaknesses. In this blog post, we will explore the types, benefits, and limitations of both non-viral and viral vectors in gene therapy.

Khalil Essani - Single Use Support

Khalil Essani

September 21, 2023

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