RoSS.pFTU XL

Plate-Based Freezing & Thawing | 500L Volume

Parallel controlled freezing and thawing of thousands of liters in biopharmaceutical manufacturing processes. The extra large scale freezing platform system is an automated plate-based freeze-thaw unit for liquid substances including vaccines, media, buffer solutions or other drug substances.

No manual handling of single-use bags required: The established RoSS.pFTU platform system is compatible with 10x50L single-use bags from any vendor.

Request a quote
RoSS.PFTU XL_Large Volume Freeze-Thaw_Single Use Support

Advantages of controlled plate-freezers

Dark blue spots indicate a higher cryoconcentration. 
Fast & controlled freezing with a plate freezer enables a homogeneous freezing result.

Advantages of controlled plate-freezers-Grafik

Description

Plate-based Freeze & Thaw platform system for controlled freezing and thawing of extra large volumes and bulk drug substances (BDS) in biopharma manufacturing processes:

  • Zero Manual Handling: Fully automated freezing and thawing process with no manual handling of single-use bags required
  • Capacity: 500L nominal volume per Batch (10x50L Bags)
  • Flexible Primary Packaging: Choose any 50L single-use bag of your choice
  • Freezes down to -90°C
  • Thawing with integrated shaker function
  • Technology: Plate-based freezer for homogeneous freezing of your product
  • Simple loading and unloading of the palette-sized rack with forklift or palette jack
  • RoSS Shell for Protection & Secondary Packaging: For best protection and optimized homogeneous freezing we recommend the use of RoSS shells for your single-use bags
  • GMP-compliant, automated, at highest possible speed and accuracy
  • Low Footprint
Get in contact now
RoSS.pFTU XL_Product Overview-2
RoSS shell 50L with RoSS.pFTU XL-4

Our customers trust in us:

fujifilm-diosynth-biotechnologies-logo
LONZA_Logo_png
Moderna_Logo_png
AGC Biologics Logo - Full Color - PNG

Fujifilm Diosynth

Lonza

Moderna

AGC Biologics

Advantages of RoSS.PFTU over other solutions in the industry

 

Plate-Freezer Platform 1 

Blast-Freezer Platform 2

RoSS.PFTU XL

Plate-Based Freeze Thaw Platform 

Comments

Fast Freezing

⁓

×

✅

The RoSS.pFTU XL achieves controlled freezing to -80°C in shortest time

Low Footprint

✔

⁓

✅

Optimized for a maximum volume on the lowest footprint needed

Vendor-agnostic infrastructure

×

×

✅

Full freedom on choice of your primary packaging supplier

Modularity & Scalability 

×

×

✅

Scalable freezing with the RoSS.pFTU plate-freezers from 1L up 500L nominal volume per batch

Minimum Manual Handling

⁓

⁓

✅

Fully automated freezing process & simple loading/unloading of the palette-size racked

Data sheet

Datasheet RoSS.pFTU XL

Filesize: 0.57 MB – Mime-Type: application/pdf

Case Study_Scalable Fast Freezing

Filesize: 1.59 MB – Mime-Type: application/pdf

Whitepaper: How Controlled & Scalable Freezing Becomes Reality

Filesize: 1.96 MB – Mime-Type: application/pdf

More solutions

RoSS.FILL Base_With Rack

RoSS.FILL Base | Single-use aseptic fill-filtration system for large volumes

Up to 1000L: Fully automated system for aseptic filling for large volume bulk drug substances.

More information
Ultra-cold storage RoSS.FRDG

RoSS.FRDG | Ultra Cold Storage Freezer

RoSS.FRDG is an ultra cold storage fridge for frozen drug substances in different sizes. The ultra cold freezer keeps the desired set point temperature down to -80°C. RoSS.FRDG offers highest storage density, is fully movable and can be modularly adapted to your individual needs.

More information
ross-shak-shaker

ROSS.SHAK | Shaker

RoSS.SHAK is your reliable shaker to regain highest quality and homogeneity of your biopharmaceuticals.

RoSS.SHAK enables constant shaking of your protein to regain homogeneity and product quality after freezing. Shakes up to 70L per run in 3 pre-defined speeds.

More information
ross-drai-drain-single-use-bags

RoSS.DRAI | Drain

Drain your single use bags at Fill & Finish site. This standalone draining rack enable controlled fluid flow while draining single-use bags. Connected peristaltic pumps enable lowest holdup volume. Multiple racks can be attached for simultaneous and continuous pooling thanks to inclination of all shelves. All disconnection types possible.

More information

More information

Whitepaper_Controlled_Scalable_Freezing_SEP22

Whitepaper: How controlled freezing enables scalability

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.

More information
Case study: How to ensure sterility in end-to-end bulk management

Case Study: How to ensure sterility in end-to-end bulk management?

The case study depicts how the implementation of Single Use Support and CPC products positively impacted on the performance of the company. Get the case study now & listen to free podcasts!

More information
Bulk drug substance management by Single Use Support

Bulk drug substance management

The following article aims to take a closer look at the term “bulk drug substance” and its meaning, as well as to investigate smart solutions to shorten the phase between development and blockbuster production. Read more about the solution for the biopharmaceutical industry!

More information
Bulk drug substance logistics with single-use technology

Drug substance logistics – Advances with single-use technologies

It is not easy to choose the right technology when it comes to developing biopharmaceutical drug products! It’s important for frozen storage and transport solutions to be safe and cost-effective at the same time, especially as drugs transition from R&D through clinical trial and to higher volume production.
 

More information

Send a request