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Plate freeze & thaw | RoSS.pFTU Mid-Scale

Plate freeze & thaw | RoSS.pFTU Mid-Scale

Single Use Support's mid scale freezer is a plate-based freeze-thaw system designed to protect your preferred single-use bag during cryogenic applications. 

The system is compatible with single-use bioprocess containers of all sizes and manufacturers and shows the best product stability results for your drug substances up to 100L. 

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Green icon of a thermometer on a transparent background demonstrating temperature control
Down to -80°C
Green icon of configuration settings on a transparent background demonstrating controlled rate freezing and thawing in biopharma
Controlled freeze-thaw
Green icon of a water droplet and an arrow on a transparent background demonstrating scalability
Up to 100L/batch

Features and benefits of RoSS.pFTU Mid Scale

  • Suitable for single-use bags up to 20L, regardless of the manufacturer
  • Total load of up to 100L with different sizes of single-use bags
  • Enables controlled freezing down to -80 °C with highest possible speed and accuracy
  • Usage for stability studies in labs and small batch sizes
  • Fully automated and cGMP-compliant, allowing seamless scale-up to RoSS.pFTU Large Scale systems
  • Combination with RoSS® shells and RoSS.KSET for optimal protection and handling of single-use bags during freezing

Our customers trust in us:

  • Graphic of two frozen single-use bags showing different freezing results
  • To demonstrate the effects of cryoconcentration, Naphthol Blue Black was used as a visual marker. The intensity of the blue coloration indicates the concentration of dissolved substances within the frozen solution.

    Slow uncontrolled freezing (A)

    In contrast, bags frozen in a static freezer show uneven solute distribution. Dark blue areas, especially in the lower regions of the bag, highlight significant cryoconcentration.


    Fast controlled freezing (B)

    Bags frozen using our plate-based controlled rate freezer show a uniform distribution of solutes. The result is a consistent, light-blue hue with a distinct white line through the center indicating minimal cryoconcentration.

Downloads

Preview of datasheet for RoSS.pFTU Mid Scale freeze-thaw unit by Single Use Support
Datasheet: RoSS.pFTU Mid Scale
Preview of datasheet for RoSS.pFTU Mid Scale freeze-thaw unit by Single Use Support
Datasheet: RoSS.pFTU Mid Scale
 
Preview of Single Use Support's whitepaper about controlled freezing with RoSS.pFTU
Whitepaper: RoSS.pFTU - Controlled scalable freezing
Preview of Single Use Support's whitepaper about controlled freezing with RoSS.pFTU
Whitepaper: RoSS.pFTU - Controlled scalable freezing
 
Preview of datasheet for RoSS.pFTU scale overview by Single Use Support
Guide: Scale overview RoSS.pFTU
Preview of datasheet for RoSS.pFTU scale overview by Single Use Support
Guide: Scale overview RoSS.pFTU
 
  • Single Use Support platforms provide insular solutions for the freeze/thaw processes of each clinical phase. Fully scalable and compatible with all batch sizes and bags from all established manufacturers – you will only require one single system from the lab to blockbuster production. From 10mL up to 50L bags and a batch size of up to 500L and more you can scale-up or down as required.

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  • Graphic of different scale-up stages for freeze-thaw systems used in biopharmaceutical manufacturing.

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