IRIS Seal | Aseptic Disconnection

Sealing single-use assemblies with improved process flexibility.

IRIS Seals are metallic pinch-pipes to safely crimp and cut single-use assemblies into two separate sterile fluid paths. 

Either as one cylindrical pinch pipe or as two compatible semicircles IRIS seals allow operators to improve process flexibility in sterile fluid management and to add to the quality of well-established sealing processes of crimping.

IRIS SUS Seal_Product Photo

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Rentschler Biopharma SE



Features of flexible single-use manifold decoupling

  • IRIS seals are cylindric metal pinch pipe allowing aseptic disconnection with crimping 
  • Withstands pressure up to 1.5 bar
  • Available in standard outer diameter sizes of tubings: 1/2“, 5/8“, 3/4“ - customization upon request
  • Suitable for cleanroom and based on international biopharmaceutical standards
  • Also available as IRIS Easy Seal - consisting of two compatible semicircles, forming a metallic pinch-pipe for crimping. Operators can clip or slide the semicircles on single-use tubings to form a metallic pipe


IRIS SUS Seal_Product Photo

IRIS SUS Seal | Crimping Single-Use Assemblies

IRIS SUS Seal is a metallic cylindrical pinch-pipe to safely crimp and cut single-use assemblies into two separate sterile fluid paths. The closed pipes for crimping must be attached to single-use assemblies in its predefined design phase before sterilization. 

IRIS Easy Seal_Product Photo (2)

IRIS Easy Seal | Crimping Single-Use Assemblies

IRIS Easy Seal is a metallic pinch-pipe to safely crimp and cut single-use assemblies into two separate sterile fluid paths. Easy Seal comes in two compatible semicircles which allows the operator to add and remove seals onsite to disconnect assemblies flexibly at the manufacturing site.

Data sheets

Click here to download technical product data sheets, case studies and more.

Datasheet_IRIS_Easy Seal

Datasheet IRIS Easy Seal

Filesize: 0.42 MB – Mime-Type: application/pdf

Case Study - Customized IRIS Single Use Assemblies

Case Study - Customized Manifolds

Filesize: 0.65 MB – Mime-Type: application/pdf

Infografic - single-use assemblies mAb

Infographic: Single-Use Assemblies in Biopharma Manufacturing

Filesize: 3.58 MB – Mime-Type: application/pdf

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