Alexander Fuchs

Therapeutic proteins hold promise in the treatment of numerous medical conditions, and progress in this field is far from being over. This is reason enough to take a general look at this class of therapeutics.

Prior to be used in diagnostics or therapeutics, proteins have to be safely stored. In this article, we will assess methods to preserve their stability upon storage.

Active pharmaceutical ingredients (APIs) are fundamental for drug products to be effective, but require special treatment – e.g. considering humidity, light, or temperature. In this article, we will highlight the different cold storage requirements of APIs, including examples and an overview of different practical approaches.

In a recent study, freezing protocols were tested with the RoSS.LN2F controlled liquid nitrogen freezer to find the optimal freezing rate for CHO-K1 cells in order to achieve maximum cell viability. 

mAb production requires high levels of expertise and precision, as well as specialized equipment. Nonetheless, there are several challenges that manufacturers have to deal with.

In many cases, antibodies need to be stored for varying time spans before further processing or administration. Hence, it is essential to mind the characteristic storage requirements of these valuable biologics.

Scale-up has to be considered already in early stages of monoclonal antibody production. But what do manufacturers have to bear in mind? We'll find out in this article.

Ultra low temperature (ULT) storage emerges as a solid rock to safeguard the cold chain. Discover cutting-edge technologies, the role of controlled freezing, and Single Use Support's solution for long-term storage of vaccines.

Scale-up in vaccine management comes with various intricacies. In this article, we will uncover some of them, along with solutions to overcome them.

Cold chain management is essential to provide safety and efficiency of various vaccines. In this article, we will discuss different cold chain solutions for optimized vaccine evelopment.

When it comes to vaccine manufacturing, companies inevitably have to bother with fluid management. In this article, we will discuss some relevant aspects of fluid management solutions for vaccine manufacturers.

Freezing small volumes extends beyond laboratory settings to include commercialized manufacturing processes for small batches in biomanufacturing, like cell banking, gene therapies utilizing viral vectors, lipid nanoparticles, and fill & finish procedures.