Alexander Fuchs

Cold chain management is essential to provide safety and efficiency of various vaccines. In this article, we will discuss different cold chain solutions for optimized vaccine evelopment.

When it comes to vaccine manufacturing, companies inevitably have to bother with fluid management. In this article, we will discuss some relevant aspects of fluid management solutions for vaccine manufacturers.

Freezing small volumes extends beyond laboratory settings to include commercialized manufacturing processes for small batches in biomanufacturing, like cell banking, gene therapies utilizing viral vectors, lipid nanoparticles, and fill & finish procedures.

Proper handling of viral vectors during storage, freezing, and thawing is crucial to maintaining their integrity and efficacy. In this article, we will explore best practices for preserving viral vectors, ensuring their stability, and maximizing their potential for various applications.

In the biopharmaceutical sector, the utilization of F-Gases is on a decline. However, the need for cryopreservation of drug substances will remain. In order to contribute to a more environmentally friendly freezing of drugs, more sustainable technologies need to be developed and applied. But is sustainable freezing even possible?

Innovative manufacturers are striving for operational excellence in as many areas of bioprocessing as possible. In return,a standardized and fully automated processes contribute to cost efficiency, patient safety, and sustainability in biomanufacturing. 

Considering the manifold applications of mRNA, it is essential to establish optimal freezing processes that maintain viability and effectiveness. In this article, we will compare different freezing methods for mRNA.

Freezing is a significant process step in the manufacturing of LNP-based products. In this article, we will therefore take a look at the impact freezing has on lipid nanoparticles.

As expert for cold chain handling in bioprocessing, Single Use Support is providing solutions to meet challenges for safe storing and shipping associated with right freezing and thawing methods and temperature control for long-term storage. Their development approach leads to innovative systems that enable manufacturers to replace manual processes with fully automated end-to-end processes that not only push efficiency but also increase output.

Freezing large volumes of drug substance can be a challenging endeavor. In this article, we will discuss main considerations as well as possible solutions for this delicate process.

Temperature plays a significant role in the production and distribution of several revolutionary biologics. But how does the pharmaceutical cold chain work, and what temperature ranges are most frequently chosen? You will find out in this article!

Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation, with several advantages for biopharma.