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Annex 1: All you need to know

Annex 1: All you need to know

GMP Annex 1, the European guideline for “Manufacture of sterile medicinal products”, has been updated in 2023. The revision’s changes have added several challenges, but also chances for manufacturers in order to comply with the new regulations....

Michael Mühlegger
Michael Mühlegger
7 trends in global vaccine development 2025

7 trends in global vaccine development 2025

Five years after the COVID pandemic, there are multi-faceted trends in global vaccine development that are promising for patients. Vaccine manufacturing and development have been key to improving human health and combating diseases such as poli...

Alexander Fuchs
Alexander Fuchs
Seed train intensification - the next big step in biopharma?

Seed train intensification - the next big step in biopharma?

Seed train intensification is an approach in upstream bioprocessing that is gaining more and more attention. With the growing demand for new drugs, manufacturers have to ensure both efficient and flexible production processes. While generally a...

Khalil Essani
Khalil Essani
Lentiviral vector manufacturing: Old but gold gene therapy viruses?

Lentiviral vector manufacturing: Old but gold gene therapy viruses?

Despite the fact that lentiviral vectors have been around some decades, the demand for scalable and effective manufacturing methods now rises in tandem with the need for innovative medicines. Due to their special advantages, lentiviral vectors hav...

Michael Eder
Michael Eder
Oligonucleotide manufacturing – challenges & solutions

Oligonucleotide manufacturing – challenges & solutions

Oligos - what are they? Oligonucleotides (also referred to as oligos) are short nucleic acid sequences, made up of a strand of nucleic acid, either DNA or RNA. They represent an increasingly important growth area for the biopharmaceutical manufact...

Michael Mühlegger
Michael Mühlegger
Oligonucleotides simply explained

Oligonucleotides simply explained

What are oligonucleotides? Oligonucleotides (also referred to as oligos) are short nucleic acid polymers, made up of a strand of DNA or RNA. They are synthetically made and used for a variety of research, diagnostics, and therapeutic applicatio...

Michael Mühlegger
Michael Mühlegger
DMSO: Freezing Cells

DMSO: Freezing Cells

What is DMSO? DMSO, or dimethyl sulfoxide, is a colorless liquid that is used for cell preservation. Thanks to its unique properties, it has found its way into laboratories worldwide. DMSO plays a vital role in protecting cells when temperatures d...

Khalil Essani
Khalil Essani
Vaccine manufacturing: Introduction to the process from development to large-scale production

Vaccine manufacturing: Introduction to the process from development to large-scale production

Vaccine manufacturing is a complex journey, merging scientific breakthroughs with global necessity. From the identification of antigens to large-scale production and the use of cutting-edge solutions, this journey reflects the continuous pursui...

Alexander Fuchs
Alexander Fuchs
Sustainable Practices: The Green in Single Use Support

Sustainable Practices: The Green in Single Use Support

Environmental impact from headquarters and beyond Single Use Support is committed to sustainability and environmental responsibility in our business operations. We believe that our innovative single-use technologies can contribute to the reduct...

Michael Mühlegger
Michael Mühlegger
Sustainable Freezing in Biopharma: An Exploration of Natural Gas Usage

Sustainable Freezing in Biopharma: An Exploration of Natural Gas Usage

In the biopharmaceutical sector, the utilization of F-Gases, also known as fluorinated greenhouse gases, is on a decline. However, the need for cryopreservation of drug substances will remain. In order to contribute to a more environmentally frien...

Alexander Fuchs
Alexander Fuchs
Start Pharma 4.0: Examples to Advance Ultra-Cold Storage of Drug Substances

Start Pharma 4.0: Examples to Advance Ultra-Cold Storage of Drug Substances

Pharma 4.0 is no longer a thing of the future. Industry 4.0 for biopharmaceutical manufacturing is here now.  Innovative manufacturers are striving for operational excellence in as many areas of bioprocessing as possible. In return, they will bene...

Alexander Fuchs
Alexander Fuchs
Cell cryopreservation preparation process

Cell cryopreservation preparation process

Cryopreservation is a critical procedure that includes the cooling and preservation of frozen cells at extremely low temperatures. This process is fundamental in various scientific and medical applications, facilitating long-term storage withou...

Claus Exenberger
Claus Exenberger