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Interview: Trends with Single-Use Bottles in Bioprocessing
One could read a lot about single-use bags in biopharmaceutical industry as a primary packaging in bioprocessing in the previous last years. The rise of bags has become more relevant, since they largely replaced single-use bottles. Nevertheless, s...
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Interview: Trends with Single-Use Bottles in Bioprocessing
One could read a lot about single-use bags in biopharmaceutical industry as a primary packaging in bioprocessing in the previous last years. The rise of bags has become more relevant, since they largely replaced single-use bottles. Nevertheless, s...
From carboys to rigid containers: what are the top single-use bottles in biopharma today?
Despite the popularity of single-use bags for primary packaging, single-use bottles remain critical for storing, transferring, and sampling media, buffers, and drug substances throughout the biomanufacturing workflow. These sterile, reliable, and ...
An operator’s burden: Why manual bottle filling puts biomanufacturers at risk
The hidden risk in biomanufacturing Manual bottle filling in biopharmaceutical production is more than a routine task - it’s a high-stakes responsibility. From upstream cell culture to downstream purification, every step is tightly controlled - un...
Understanding the Development and Manufacturing Process of Biosimilars
The development process for biosimilars involves an extensive testing period in order to establish similarity to the reference biologic. To ensure that the drug doesn’t have unwanted side effects, there is a broad regulatory framework developers o...
Fluid management and freeze thaw solutions for biosimilar production
The growing demand for biosimilars and significant increases in the biosimilar market call for innovative solutions for their fluid management and freeze thaw processes. This relates to steps like filling and filtration, freezing and thawing, a...
Biologic Drug Development: A Comprehensive Introduction
Biologics are a comparatively new class of drugs, nonetheless based on an ancient principle: utilizing living organisms to obtain substances that positively affect health. This approach, however, has expanded from using, e.g., plant parts for cura...
Plate freezing: best approach for freezing biopharmaceuticals
Plate freezing is a process where a product’s temperature is reduced by the means of contact with cold surfaces. Thus, a defining step in the freeze-thaw process for conservation. Things to know about plate freezing techniques Although pl...
Who manufactures monoclonal antibodies? Overview of mAb companies
Monoclonal antibody production is one of the most thriving branches of the pharmaceutical industry. The enhanced interest in antibody production is due to the success of antibody treatments which are used to trigger an immune response against infe...
Evolving Aseptic Filling in Biomanufacturing
In the dynamic landscape of pharmaceutical manufacturing, the journey from laminar flow to automated fluid management has been nothing short of transformative. This evolution, marked by innovation and adaptability, has reshaped the way smaller vol...
mRNA vaccines: How to safely ship and store them
In the past few years, awareness of the mRNA vaccine supply chain has increased considerably, both in the pharma industry and among the wider public. These vaccines, including lipid nanoparticles and other components, require the highest level of ...
Fluid management in biopharma: Advantages of single-use systems
Fluid management in biopharma has changed considerably in recent years. With the advances in life science and the related healthcare adaptations, the manufacturing and supply chain divisions of biopharmaceutical companies are going through a major...
Bulk drug substance management
With the rising need for novel therapies - and, based on the changes in the disease landscape as most currently highlighted by COVID - the global biopharmaceutical industry is evolving, and market needs are shifting. We are seeing an increasing...