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Interview: Trends with Single-Use Bottles in Bioprocessing
One could read a lot about single-use bags in biopharmaceutical industry as a primary packaging in bioprocessing in the previous last years. The rise of bags has become more relevant, since they largely replaced single-use bottles. Nevertheless, s...
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Dual Sourcing: Strengthening the Pharmaceutical Supply Chain for Single-Use Assemblies
Single Sourcing vs. Dual Sourcing Do you remember when lead times were months instead of weeks? During the COVID-19 pandemic, biomanufacturers faced several significant supply chain challenges: Lockdowns and restrictions led to disruptions in ...
Bioburden Study: Does RoSS affect cleanroom sterility?
RoSS® is the safety standard for any single use bag. “Robust Storage and Shipping” is an innovation from Single Use Support providing a protection for single use bags to avoid product loss of highly valuable biopharmaceuticals. It can be applie...
Case Study: Reducing product loss | Bag-independence
The choice of single-use bioprocess containers in biopharmaceutical handling has had consequences for the performance and requirements in biomanufacturing until now. Lack of compatibility and inflexibility of platform systems have determined futur...
Defying the shortages in single-use manifold assemblies
Single-use components might not be considered as the most essential parts in biopharmaceutical manufacturing. However, they are quite capable of temporarily paralyzing the entire production of biopharmaceuticals on-site. Procurement bottlenecks of...
Customizable Manifolds solutions and its advantages
In order to comply with the versatile requirements of today’s market, flexibility and the option to customize are key whilst maintaining availability and short lead times. This is true for many areas, not least when it comes to the ever-growing nu...
Protecting single-use bags to foster their progress
Twenty years ago there was only steel. Biopharmaceutical manufacturing has been conducted by fixed stainless-steel installations for a long time. Pharmaceutical products were produced in rigid, inflexible vessels and pipings by cell culturing a...
Sterile Connectors for use in Pharma
Manufacturers of aseptic single-use connectors: Their advantages in an overview Aseptic connectors link important medical applications with one another. Preferrably easy and quick to use and it must grant sterility, even if the environment around ...
CDMO in Biopharma: Opportunity or risk?
In this article, we will discuss the differences between CMOs (contract manufacturing companies) and CDMOs (contract development and manufacturing companies), the characteristics and types of them, the services that they typically offer, the oppor...
Mission completed – and now? What to do with the RoSS® Shell after use
Once Single Use Support's RoSS shells, the secondary packaging containers for single use bags, have fulfilled their duty and protected valuable, possibly life-saving biopharmaceuticals on their way from the manufacturer’s site to where they have b...
Case Study: Reducing product loss | Cost-efficiency
Biopharmaceutical companies have largely accepted a certain level of product loss when managing drug substances in single-use systems - unaware that solutions exist to streamline process steps and dramatically diminish product loss . The breaking ...
Upstream intensification from lab to mAb manufacturing
Upstream process intensification is something you currently hear a lot in the context of upstream bioprocessing (USP) optimization. One of the upstream intensification processes being addressed is seed train intensification. This is the use of ...
Stressing Cells: The Role of Cryoprotectants in ATMP Cryopreservation
In cell and tissue therapies, living cells are used to treat previously chronic diseases, like cancer forms, arthritis, or certain autoimmune disorders. To be effective, the living therapeutic product requires administration with a sufficient c...