In cell and tissue therapies, living cells are used to treat previously chronic diseases, like cancer forms, arthritis, or certain autoimmune disorders. To be effective, the living therapeutic product requires administration with a sufficient c...
Cryopreservation is a critical procedure that includes the cooling and preservation of frozen cells at extremely low temperatures. This process is fundamental in various scientific and medical applications, facilitating long-term storage withou...
As cell and gene therapies (CGT) continue to advance, single-use systems have become essential for maintaining the safety and effectiveness of these intricate biological products. These systems not only improve sterility but also simplify manufact...
Cell viability is one of the cell product quality and regulatory parameter that determines therapeutic efficacy. For example, the FDA mandates a viability threshold of ≥ 80% for the release of CAR T cells. Nevertheless, in clinical trials and in ...
Improving Cryogenic Freezing of a Mammalian Cell Line A study was conducted aiming to optimize the cryogenic freezing process of CHO-K1 cell line using an innovative controlled rate liquid nitrogen freezer (RoSS.LN2F). The mammalian cells were fil...
Advanced cell and gene therapies, such as autologous therapies, exhibit certain specific requirements. The scale of such therapies is very different from what we typically see in conventional biopharmaceutical manufacturing processes in commercial...
Modular filling enabling process flexibility for viral vector manufacturing We are thrilled to unveil our latest customized innovation within the product range of automated aliquoting systems, RoSS.FILL. This groundbreaking solution is set to r...
Cryopreservation involves the preservation of cells, tissues, or other biological constructs by cooling them to extremely low temperatures. The preservation of cells at cryogenic temperature can be achieved using different techniques. This is far ...
Cryopreservation describes methods to preserve living organisms and biological materials at very low temperatures. Central to this process is the use of liquid nitrogen, enabling successful cryogenic freezing and cryopreservation, opening possibil...
Cell viability is an important topic in cell banking, as it expresses the amount of healthy cells in a sample and is counted among the most important CQAs (Critical Quality Attributes), determining the quality of biological products. In order to e...
Cell viability is crucial in cell banking and scientific applications. It refers to the percentage of live and healthy cells to the total number of cells in a sample, indicating cell health and functionality. Ensuring high cell viability is vital ...
Cell viability and cytotoxicity are frequent terms in biology and the biopharmaceutical industry. Cell viability describes how many cells are alive and functioning, while cytotoxicity refers to the ability of a substance to damage or kill cells. B...
