In cell and tissue therapies, living cells are used to treat previously chronic diseases, like cancer forms, arthritis, or certain autoimmune disorders. To be effective, the living therapeutic product requires administration with a sufficient c...
Cell viability and cell proliferation are two fundamental concepts in the realms of science and medicine that play a crucial role in understanding the behavior of cells. While cell viability describes the amount of living and functioning cells in ...
You may have come across the term “autologous” before in the context of stem cell therapy. Autologous stem cell transplantation is a type of cellular therapy that uses the patient's own stem cells to treat various types of blood cancers such as le...
Allogeneic cell therapy is a type of stem cell therapy that uses stem cells from a donor to treat a recipient. When it comes to treating various medical conditions, including blood disorders and cancer, the field of regenerative medicine has intro...
In these years, we are witnessing the advent of a new era in medicine and pharma. Recent breakthrough advances in life sciences such as immunotherapy, next generation sequencing and cell and gene therapies have sparked an unbelievable acceleration...
Mastering the complex CAR T manufacturing process and the associated supply chain challenges in the cell and gene area are the major bottlenecks during the large-scale commercialization of highly promising CAR T cell products. This autologous ...
Gene therapy manufacturing continues to cause a stir in the biopharma industry. Gene therapies have become a highly promising field of groundbreaking next generation treatment approaches that use personalized therapies for rare diseases and allow ...
Comparing autologous vs allogeneic cell therapies, it becomes apparent that they share both defining methodological key elements as well as various fields of application, including most innovative cancer therapies, there are significant difference...
CAR T-cell therapy is a promising approach in cancer treatment. The therapy shows huge potential for patients suffering from acute lymphoblastic leukemia who thus far had a poor prognosis: Thanks to the emergence of CAR T-cell therapy, the 5-year ...
The logistics branches of biopharma companies experience a major paradigm shift. The supply chains for conventional small molecule drug products and biologics involve the acquisition of raw materials, the manufacturing process of pharmaceutical su...
Advanced therapy medicinal products (ATMPs) are medicines for human use that are based on genes, tissues or cells. Accordingly, they can be classified into three main types, namely gene therapy tissue engineered- and somatic-cell therapy medicin...
Cell and gene therapy (CGT in short) is a new and promising type of immunotherapy for patients suffering from certain types of cancer and lymphoma/leukemia. It is among the treatments of Advanced Therapy Medicinal Products, in short ATMP. Any ex-v...
Biopharma solution provider Single Use Support announces an order from Genezen, a cell and gene therapy Contract Development and Manufacturing Organization (CDMO). The Indianapolis-based CDMO has ordered RoSS.FILL CGT to fill lentiviral vectors in...
