Despite the fact that lentiviral vectors have been around some decades, the demand for scalable and effective manufacturing methods now rises in tandem with the need for innovative medicines. Due to their special advantages, lentiviral vectors hav...
AAV production has become increasingly significant over the past ten years: The Adeno-associated virus vector-based gene therapy is currently the only in-vivo gene therapy approved in the US and Europe. With adeno-associated virus being a popular ...
The challenges in viral vector production are many. The manufacturing process is complex and often demands more flexibility than traditional techniques and devices can offer. And while the safe handling AAV vectors is already difficult at smaller ...
Gene therapy holds the promise of revolutionizing medical treatments by harnessing the power of viral vectors to deliver therapeutic genes into the genome of patients. This innovative approach has the potential to address a myriad of genetic di...
Services for AAV packaging – the procedure of encapsulating a gene of interest within an AAV – are, among other AAV production services, highly requested, given the complexity of the overall AAV manufacturing process. Nevertheless, adeno-associ...
When designing gene therapies, the choice between non-viral and viral vectors plays an important role in determining the success and safety of therapeutic interventions. Non-viral vectors offer unique advantages, while viral vectors have their ...
Among the various vaccines available, viral vector vaccines are among the most innovative approaches. They use different viruses (viral vectors) that are able to deliver genetic material into the body, and can even enter cells to use their machine...
In the manufacturing of viral vectors aseptic aliquotation is a critical process step. It is the practice of dividing one larger container of vectors into smaller samples. It is important to generate the same amount of smaller aliquots whilst main...
Vaccines are vital in the fight against infectious disease and for protecting public health. Two prominent vaccine technologies that have emerged are viral vector vaccines and mRNA vaccines. These innovative technologies hold significant potential...
Viral vector manufacturing is one of the most innovative advancements in gene therapy, with the potential to transform medical treatments and improve people’s lives. However, scalability is a significant challenge that slows this field’s progress....
Viral vectors like Adeno-associated viruses (AAVs) are popular vectors for gene therapy and vaccines. And yet, there is product loss due to leakages of primary packagings or other mishandling of fluids. In order to deliver high-quality and viable ...
Viral vectors and specifically Adeno-Associated Virus (AAV) vectors have gained significant prominence in gene therapy and biotechnology research due to their ability to efficiently deliver genetic material into target cells. Proper handling of vi...
