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Precision Fluid Management for ADCs
The hidden gaps in the fill-to-freeze workflows
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In high potent active pharmaceutical ingredients (HPAPI) and antibody-drug conjugate (ADC) manufacturing, the most critical risks are often not visible at first glance. While much attention is given to payload potency and containment concepts, it...
Cell viability is an important topic in cell banking, as it expresses the amount of healthy cells in a sample and is counted among the most important CQAs (Critical Quality Attributes), determining the quality of biological products. In order to e...
Cell viability is crucial in cell banking and scientific applications. It refers to the percentage of live and healthy cells to the total number of cells in a sample, indicating cell health and functionality. Ensuring high cell viability is vital ...
Cell viability and cytotoxicity are frequent terms in biology and the biopharmaceutical industry. Cell viability describes how many cells are alive and functioning, while cytotoxicity refers to the ability of a substance to damage or kill cells. B...
Cell viability and cell proliferation are two fundamental concepts in the realms of science and medicine that play a crucial role in understanding the behavior of cells. While cell viability describes the amount of living and functioning cells in ...
The function of mRNA (messenger RNA) determines many aspects of molecular biology, considering that it plays an essential role in protein synthesis. As the intermediary messenger between DNA and proteins, mRNA carries the genetic information ne...
Messenger RNA (mRNA) is a vital player in the intricate process of gene expression and protein synthesis. It acts as a messenger, carrying genetic information from the DNA to the protein-building machinery in the cell. With the advent of mRNA vacc...
mRNA manufacturing, or the production of messenger RNA (mRNA), has quickly become one of the most discussed topics in the biotechnology sphere. While the science of mRNA has been researched for quite some time, its application in drug manufacturin...
mRNA (messenger RNA) technology has emerged as a groundbreaking innovation with vast potential across various fields, including healthcare and biologics. However, it also raises questions on the ideal freezing, storage and transport conditions for...
Freezing mRNA is a crucial step in messenger RNA manufacturing, balancing product quality, cost-effectiveness, process safety, and efficiency. Traditional methods can be inefficient and error-prone, while there are innovative solutions that can...
Lipid nanoparticles (LNPs) are nanoparticles that consist of solid and liquid lipids and are stabilized by emulsifiers. They are efficient drug delivery systems which carry drug substances to target cells, where they become absorbed and are rel...
Advancing fluid management with single-use technology Fluid management is a cornerstone in mRNA manufacturing and therapeutics, where maintaining product quality and safety is of utmost importance. Advances in mRNA technology have revolutionize...
The use of lipid nanoparticles (LNPs) has gained significant attention due to their potential applications in drug delivery systems. LNPs have shown promise in encapsulating and delivering various therapeutic molecules, such as nucleic acids, p...
