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The hidden gaps in the fill-to-freeze workflows
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Most bulk drug substances are filled into 2D single-use bags for one reason: they are about to be frozen. Yet filling and freezing are often treated as separate unit operations. Filling systems are selected for accuracy and throughput. Freeze-thaw...
Cell bank manufacturing is an essential part in the production of biopharmaceuticals like antibody drugs or vaccines. A fully functioning, characterized master cell bank is the basis for everyone who wants to ensure reproducibility of a successful...
There are a number of different types of cell banks, and irrespective of which one we are talking about, cell banking requires expertise, appropriate quality control and constant monitoring. In addition to special equipment, the right set-up and i...
While all working cell banks are derived from a master cell bank, the two different types serve different purposes. A master cell banking system has an overarching function, so to speak, as its main purpose is the production of enough viable cells...
Cryopreservation of cells is a necessary step in drug manufacturing and development which relies on a constant cell supply and cell reproducibility. By freezing cell lines at cryogenic temperatures, different cell types can be stored for future us...
Cell banking is a crucial process in biopharmaceutical production, ensuring the preservation and availability of valuable cell lines. Proper storage of cells and maintenance of a cell bank is essential to uphold the integrity and reproducibility o...
At the core of cutting-edge research and biopharmaceutical production lies the crucial need to preserve and store precious cell lines, ensuring their availability for future studies and therapeutic applications. Cell banking plays a critical role ...
Cell banking plays a key role in securing valuable cell lines and biological resources for future research and applications in the field of biotechnology. Researchers and scientists rely heavily on cells as building blocks for their studies, sp...
In the field of life sciences, the cryopreservation of cells plays a pivotal role in advancing research and development. By freezing cells, scientists can safely store valuable cell lines and primary cells, ensuring their long-term storage and via...
Cell banking holds the key to unlocking countless possibilities in research and biopharmaceutical production. By preserving and storing valuable cell lines, cell banking ensures a stable and consistent source of cells for various applications. In ...
Biopharmaceutical products are valuable and often highly sensitive substances. Their active pharmaceutical ingredients (APIs) must be maintained at the highest-possible quality at all times during their production, transport, and storage. This req...
Among the key innovations of the biopharmaceutical industry over recent decades, the cryovessel stands out as a critical component in the process of freezing biopharmaceuticals. In this blog post, we delve into the background of cryovessels and th...
Khalil Essani is Techical Product Owner - Sterile Consumables at Single Use Support. As single-use system enthusiast, he has led several projects to develop and deliver single-use assemblies. Working closely with various biomanufacturers he strive...
