Freezing drug substances to ultra-cold temperatures is a standard step in biopharmaceutical manufacturing. Yet, beyond simply cooling, it’s the critical quality attributes (CQA), like product safety, consistency, and process efficiency, that trul...
Biopharmaceutical companies have largely accepted a certain level of product loss when managing drug substances in single-use systems - unaware that solutions exist to streamline process steps and dramatically diminish product loss . The breaking ...
Upstream process intensification is something you currently hear a lot in the context of upstream bioprocessing (USP) optimization. One of the upstream intensification processes being addressed is seed train intensification. This is the use of ...
In cell and tissue therapies, living cells are used to treat previously chronic diseases, like cancer forms, arthritis, or certain autoimmune disorders. To be effective, the living therapeutic product requires administration with a sufficient c...
GMP Annex 1, the European guideline for “Manufacture of sterile medicinal products”, has been updated in 2023. The revision’s changes have added several challenges, but also chances for manufacturers in order to comply with the new regulations....
Five years after the COVID pandemic, there are multi-faceted trends in global vaccine development that are promising for patients. Vaccine manufacturing and development have been key to improving human health and combating diseases such as poli...
Seed train intensification is an approach in upstream bioprocessing that is gaining more and more attention. With the growing demand for new drugs, manufacturers have to ensure both efficient and flexible production processes. While generally a...
Despite the fact that lentiviral vectors have been around some decades, the demand for scalable and effective manufacturing methods now rises in tandem with the need for innovative medicines. Due to their special advantages, lentiviral vectors hav...
Oligos - what are they? Oligonucleotides (also referred to as oligos) are short nucleic acid sequences, made up of a strand of nucleic acid, either DNA or RNA. They represent an increasingly important growth area for the biopharmaceutical manufact...
What are oligonucleotides? Oligonucleotides (also referred to as oligos) are short nucleic acid polymers, made up of a strand of DNA or RNA. They are synthetically made and used for a variety of research, diagnostics, and therapeutic applicatio...
What is DMSO? DMSO, or dimethyl sulfoxide, is a colorless liquid that is used for cell preservation. Thanks to its unique properties, it has found its way into laboratories worldwide. DMSO plays a vital role in protecting cells when temperatures d...
Vaccine manufacturing is a complex journey, merging scientific breakthroughs with global necessity. From the identification of antigens to large-scale production and the use of cutting-edge solutions, this journey reflects the continuous pursui...
Environmental impact from headquarters and beyond Single Use Support is committed to sustainability and environmental responsibility in our business operations. We believe that our innovative single-use technologies can contribute to the reduct...
