Enhancing Process Flexibility With Automated Filling

Michael Eder
Michael Eder

Addressing Challenges in Aseptic Filling

Accurate and efficient filling of biopharmaceuticals in primary packagings, such as single-use bags and bottles, is crucial. 

Even the smallest deviations in the filling volume can have a huge impact on the production process, or finally on the patient‘s therapy. For example, if a liquid needs to be frozen for
transport, overfilling or an inconsistent volume of single-use bags seriously increases the risk of bag leakage and product loss. In most cases, it is absolutely important that a patient receives exactly the same volume of the medication per injection. Operational errors in aliquotation processes often occur due to manual intervention or limitations. 

Highest Accuracy: Single Use Support with Sonotec

In order to implement flow sensors with the highest precision, Single Use Support decided to implement SONOTEC's SONOFLOW CO.55 V3.0 ultrasonic flowmeters on its RoSS.FILL platforms for dispensing small volumes. The sensors are simply clamped onto the tubing and measure without contact, thus eliminating the risk of contamination or leakage.

Discover the full benefits of SONOTEC's collaboration with Single Use Support for biopharmaceutical fluid management in the new application note.

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Preview of Single Use Support's app note about automated and aspetic filling with sonotec filling sensors

Download app note

App note: Enhancing process flexibility with automated filling

Enhancing Process Flexibility and Filling Accuracy With Automated Filling. For low volume dispensing at a commercial scale, accuracy and repeatability are essential. To achieve a filling accuracy range of even less than ± 1 mL with the RoSS.FILL platform, Single Use Support decided to implement SONOTEC‘s SONOFLOW CO.55 V3.0 ultrasonic flow meters. 

Michael Eder
Michael Eder Senior Marketing Manager

Michael Eder, MA, is Senior Marketing Manager at Single Use Support. He is expert in pharma and health communication with his 10+ years experience in pharma. After completing his master's degree in International Healthcare Management at MCI The Entrepreneurial school in Innsbruck, he has gained experience in the pharmaceutical field manufacturing and commercialization of OTC and RX drugs. Michael creates articles about Freeze Thaw applications and Platform solutions from Single Use Support and is the author of current news with Single Use Support worldwide.