Advanced fluid & cold chain management of bottles
From clinical to commercial without compromise
Single Use Support’s bottle solutions ensure safe, scalable handling of drug substance, media, and buffers. From closed-system filling to controlled freezing and validated protection, we help you secure every drop.
Challenges in bottle-based workflows in biopharma:
Scalable solutions for your bottle processes
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Fast & homogeneous aliquoting
RoSS.FILL Bottle: Automated aseptic filling platforms to enable accurate, fast and safe dispensing into bottles. Introducing 21 CFR Part 11 and GMP-compliance paired with high filling accuracy help advance fluid management processes.
IRIS single-use assemblies are customized off-the-shelf fluid transfer tubing sets to provide an aseptically closed system and qualified bottle fluid path.
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Controlled freezing & thawing
RoSS.BLST is a GMP-compliant system for blast freezing & thawing of drug substances. It is suitable for any primary packaging from all manufacturers and allows freezing and thawing within a temperature range of -80°C to +40°C.
The modular and mobile internal rack system offers maximal flexibility and enables a simple transfer from blast freezing to ultra-cold storage.
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Best container integrity
Bottle RoSS protects the tubing on bottles protected at glass-like sub-zero temperatures with the help of a soft 3D foam which hardens at frozen state.
Any manufacturer of rigid containers from 500mL to 10L can be protected with Bottle RoSS. Its dimensions incl. height is adjustable according to tubing/connectors attached upon request.
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Case Study: Automating the process of filling media into bottles
More information
Interview: Trends with Single-Use Bottles in Bioprocessing
One could read a lot about single-use bags in biopharmaceutical industry as a primary packaging in bioprocessing in the previous last years. The rise of bags has become more relevant, since they largely replaced single-use bottles. Nevertheless, s...
From carboys to rigid containers: what are the top single-use bottles in biopharma today?
Despite the popularity of single-use bags for primary packaging, single-use bottles remain critical for storing, transferring, and sampling media, buffers, and drug substances throughout the biomanufacturing workflow. These sterile, reliable, and ...
An operator’s burden: Why manual bottle filling puts biomanufacturers at risk
The hidden risk in biomanufacturing Manual bottle filling in biopharmaceutical production is more than a routine task - it’s a high-stakes responsibility. From upstream cell culture to downstream purification, every step is tightly controlled - un...
