Freezing drug substances to ultra-cold temperatures is a standard step in biopharmaceutical manufacturing. Yet, beyond simply cooling, it’s the critical quality attributes (CQA), like product safety, consistency, and process efficiency, that trul...
The global distribution of pharmaceuticals is complex and demanding, requiring precise handling and storage of sensitive products. With the rise of personalized medicine and the increasing globalization of the industry, the need for safe and effic...
Cryogenic freezing is a necessary process for the preservation of molecules, cells, genetic material, blood, and tissues. Single-use technologies enable protection of such substances from contamination and failure and preserve them for long-term s...
With the emergence of many innovative approaches in the biopharmaceutical industry in recent years, life sciences companies have needed to put increasing efforts into pharmaceutical cold chain management. Many newly developed, highly sensitive ...
When dealing with the proper handling of some of the most innovative biologics – whether they are already on the market or still in the stage of clinical trials –, ultra-cold freezing and storing is a necessity. Since many pharmaceutical substanc...
Hybrid solution for drug freezing and thawing involve the use of both primary packagings, single-use bioprocess containers and bottles, the latter also known as rigid containers or PE containers. Biopharmaceutical manufacturers and CMOs typical...
In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated. Controlling the freezing behavior of drug substance is the ultimate goal in pharmaceutical manufacturing. It opens do...
"Scalability" is and will remain an important topic in Biopharma. No matter what area of application, it will be necessary to scale-up or down at some point. Scaling-up from doing research in small lab environments with a handful of scientists to ...
Suppliers for freeze thaw platforms are highly requested, as players in the biopharmaceutical industry are dealing with a variety of highly valuable and very sensitive goods. And in order to preserve their properties, bulk drug substances are c...
How x-ray views affirm plate-based freezers as spearheaded freezing technology in Biopharma One of the most critical process steps for biopharmaceuticals is freezing the product in single use bags to sub-zero. No matter if companies are freezing b...
There are many choices on how to freeze your biopharmaceutical bulk material. Some freezing methods focus on deep freezing while others long-term storage to hold temperature. But what is the most effective and efficient approach for my cold chain?...
When it comes to the manufacturing and development of biopharmaceutics, single-use bioprocess container exhibit a vast number of advantages for cold chain logistics: Handling is easy, costs – both for acquisition, storage and transport – are low, ...
