Simplifying Cryopreservation of Cell Monolayers

Khalil Essani
Khalil Essani

Cell monolayers are an ideal method and widely used in the discovery of new drug compounds and the study of cell biology. Until now, there was no cryopreservation technology available to store cell banks pre-plated commercially. The conventional approach of cell-based assay workflow was time- and resource-consuming. Now, the cryoprotectant technology CryoShieldTM from CryoLogyx together with the controlled and scalable plate freeze-thaw platform RoSS.pFTU from Single Use Support, mark a revolution in commercial cell banking: Cryopreserved Thaw and Use Cell Plates improve the process of preparing cell cultures to carry out cell-based experiments to a large extent. 

Study results confirm a consistent and uniform high ratio of live cell recovery after cryopreservation of cells with accelerated cell-based process workflow. 


"Convenient, ready to use from the freezer, cell-based assays could accelerate and simplify the discovery of pharmaceutically active compounds, biocompatibility testing, assay development and discovery of cell signalling and disease pathways."Convenient, ready to use from the freezer, cell-based assays could accelerate and simplify the discovery of pharmaceutically active compounds, biocompatibility testing, assay development and discovery of cell signalling and disease pathways."
Khalil Essani, Single Use Support

Labs benefit greatly from on demand access to cell-based assays by simplified workflows and highest flexibility. This on demand access to cell-based assays increases significantly the range and amount of experiments they can carry out in the same time.

Read the application note to learn more about the effect of controlled and scalable freezing to achieve advanced process solutions with cryopreserved pre-plated cell monolayers. 

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Preview of an app note about cell monolayer cryopreservation

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App Note: Cell Monolayer Cryopreservation

Discover how CryoShield™ and RoSS.pFTU enable the cryopreservation of adherent cell monolayers directly in microtiter plates. This application note outlines how this innovation eliminates the need for lengthy cell culture preparation, reduces lab overhead, and accelerates research workflows. Ideal for labs seeking ready-to-use, thaw-and-go cell-based assays for drug discovery and assay development.

App Note: Cell Monolayer Cryopreservation
 
Khalil Essani
Khalil Essani Technical Product Owner of Sterile Consumables

Khalil Essani is Technical Product Owner of Sterile Consumable at Single Use Support. Scientist through and through he develops single-use technologies to further advance the biopharmaceutical industry during its shift towards single-use systems. Based on his extensive expertise and graduate in bioprocessing and biotechnology Khalil authors several publications. At Single Use Support he focuses on sterile products in the field of fluid and cold chain management.