Freezing drug substances to ultra-cold temperatures is a standard step in biopharmaceutical manufacturing. Yet, beyond simply cooling, it’s the critical quality attributes (CQA), like product safety, consistency, and process efficiency, that trul...
Cell viability and cell proliferation are two fundamental concepts in the realms of science and medicine that play a crucial role in understanding the behavior of cells. While cell viability describes the amount of living and functioning cells in ...
David Seifert is Teamlead of Sales Application Engineering of Single-Use Assemblies at Single Use Support. As single-use system enthusiast, he has led several projects to deliver single-use assemblies. Sometimes within only 16 days – from drawing ...
The function of mRNA (messenger RNA) determines many aspects of molecular biology, considering that it plays an essential role in protein synthesis. As the intermediary messenger between DNA and proteins, mRNA carries the genetic information ne...
Messenger RNA (mRNA) is a vital player in the intricate process of gene expression and protein synthesis. It acts as a messenger, carrying genetic information from the DNA to the protein-building machinery in the cell. With the advent of mRNA vacc...
mRNA manufacturing, or the production of messenger RNA (mRNA), has quickly become one of the most discussed topics in the biotechnology sphere. While the science of mRNA has been researched for quite some time, its application in drug manufacturin...
mRNA (messenger RNA) technology has emerged as a groundbreaking innovation with vast potential across various fields, including healthcare and biologics. However, it also raises questions on the ideal freezing, storage and transport conditions for...
Freezing mRNA is a crucial step in messenger RNA manufacturing, balancing product quality, cost-effectiveness, process safety, and efficiency. Traditional methods can be inefficient and error-prone, while there are innovative solutions that can...
Lipid nanoparticles (LNPs) are nanoparticles that consist of solid and liquid lipids and are stabilized by emulsifiers. They are efficient drug delivery systems which carry drug substances to target cells, where they become absorbed and are rel...
Advancing fluid management with single-use technology Fluid management is a cornerstone in mRNA manufacturing and therapeutics, where maintaining product quality and safety is of utmost importance. Advances in mRNA technology have revolutionize...
The use of lipid nanoparticles (LNPs) has gained significant attention due to their potential applications in drug delivery systems. LNPs have shown promise in encapsulating and delivering various therapeutic molecules, such as nucleic acids, p...
In the world of pharmaceutical research and development, lipid nanoparticles (LNPs) have emerged as a promising platform for the delivery of various therapeutic agents. These LNPs offer exceptional benefits such as improved drug encapsulation, ...
Unlocking Potential: From outdated CryoVessels to state-of-the-art Plate Freezers The freezing method with multi-use cryogenic containers, also called cryovessels, has been used for decades. The open stainless-steel container is still largely in u...
