Freezing drug substances to ultra-cold temperatures is a standard step in biopharmaceutical manufacturing. Yet, beyond simply cooling, it’s the critical quality attributes (CQA), like product safety, consistency, and process efficiency, that trul...
Among the various vaccines available, viral vector vaccines are among the most innovative approaches. They use different viruses (viral vectors) that are able to deliver genetic material into the body, and can even enter cells to use their machine...
In the manufacturing of viral vectors aseptic aliquotation is a critical process step. It is the practice of dividing one larger container of vectors into smaller samples. It is important to generate the same amount of smaller aliquots whilst main...
Vaccines are vital in the fight against infectious disease and for protecting public health. Two prominent vaccine technologies that have emerged are viral vector vaccines and mRNA vaccines. These innovative technologies hold significant potential...
Viral vector manufacturing is one of the most innovative advancements in gene therapy, with the potential to transform medical treatments and improve people’s lives. However, scalability is a significant challenge that slows this field’s progress....
Viral vectors like Adeno-associated viruses (AAVs) are popular vectors for gene therapy and vaccines. And yet, there is product loss due to leakages of primary packagings or other mishandling of fluids. In order to deliver high-quality and viable ...
Viral vectors and specifically Adeno-Associated Virus (AAV) vectors have gained significant prominence in gene therapy and biotechnology research due to their ability to efficiently deliver genetic material into target cells. Proper handling of vi...
Viral vectors have become a cornerstone in biotechnology. While their function is complex, they play a vital role in various areas, including gene therapy, vaccine development, and genetic research. In this article, we will provide a simple defini...
Gene therapy stands at the forefront of medical innovation that offers powerful solutions for complex genetic disorders. A critical aspect of this field is the use of Adeno-Associated Viruses (AAVs) as vectors. In this blog post, we'll show exa...
Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, ...
The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA. These vectors se...
The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages. What is an AA...
On the biopharmaceutical market, plasmid DNA manufacturing companies have become essential players, as pDNA has enabled significant advancements in biotechnology. Whether it’s gene therapy, the development of DNA vaccines, or the production of cel...
