Daniel Tischler

Director Integrated Solutions

d.tischler@susupport.com

Daniel Tischler is Director Integrated Solutions with experience in sales & business development, product line management, application engineering at Single Use Support.

Proximity to mechatronic systems and to customers were two constants for Daniel Tischler. At Single Use Support he started as a project manager. Later he provided customers technical insights as sales application engineer. Daniel was Head of Product Line Management working on new innovations for customers in the biopharmaceutical industry, before he has started as Director of Commercial Operations.

Daniel has gained 10+ years of expertise in design engineering and project management before he joined Single Use Support.

Articles written by Daniel Tischler

Bioprocessing

Filling & Freezing large volumes for fermentation in less than 8 hours

The filling and freezing of large volumes for fermentation is an essential part during different production steps in upstream and downstream processing. In the following, we will explain why it is important to act fast and how an optimization of the process can be achieved.

Daniel Tischler

March 16, 2023

Vaccines

Safe handling of bulk drug substances

When dealing with bulk drug substances, there are several risks to consider along the processing steps. Read more on the critical steps in bulk drug substance production and possible solutions – in this article.

Daniel Tischler

March 13, 2023

Reducing human error & product loss in pharmaceutical fermentation

Bioprocessing

Reducing product loss & human error in pharmaceutical fermentation

Pharmaceutical manufacturing processes, including pharmaceutical fermentation, are still prone to human error and product loss. The challenges can be overcome by moving to automated processes that eliminate the need for slow and error-prone manual handling. Adopting automated end-to-end solutions based on single-use technologies minimizes, if not eliminates, human error and product loss.

Daniel Tischler

February 28, 2023

Bioprocessing

Fermentation in the pharmaceutical industry: A complete guide

Fermentation in the pharmaceutical industry is used to cultivate microorganisms for antibiotics, therapeutic proteins, enzymes and insulin. It typically involves temperature-controlled tanks, also known as fermenters and the correct concentration of nutrients to cultivate the desired organism. Microbial and bacterial fermentation technology and the associated processes open new possibilities and are important building blocks for gene-editing, conjugates and DNA plasmids used in modern vaccine production.

Daniel Tischler

February 17, 2023

Bioprocessing

Differences between microbial fermentation & mammalian cell culture

Microbial fermentation in bacteria, yeast or fungi is, due to its benefits, preferred in the production of smaller biologics. These include peptides, proteins, cytokines, growth factors, plasmid DNA, single-domain antibodies, peptibodies and more. Continue reading...!

Daniel Tischler

February 14, 2023

Bioprocessing

Upstream processing with single-use systems

The manufacturing process of biopharmaceuticals such as monoclonal antibodies, mRNA and bioconjugates is divided into upstream and downstream processing. Manufacturers seeking reliable automation and optimization fit for scale-up are increasingly employing single-use bioreactors, titers, filtration and other components, especially during upstream.

Daniel Tischler

December 20, 2022

Single-use technology in downstream processing

Bioprocessing

Downstream processing with single-use systems

One would think that a sector like the fast-paced biomanufacturing industry could not get any faster. Yet, increased speed-to-market and ever more efficient manufacturing continue to drive product and process development. This is why single-use technologies have become increasingly popular. Read more about single-use systems for downstream processing in this article.

Daniel Tischler

December 19, 2022

Bioprocessing

What is upstream and downstream processing?

Upstream and downstream processing are two steps inherent to the production of active pharmaceutical ingredients (API) used in biopharmaceuticals. The production is challenged by increasing regulation and manufacturing costs. This calls for flexible solutions, which is why a growing number of manufacturing processes utilize single-use systems

Daniel Tischler

December 19, 2022

Freeze & Thaw

How Hybrid Freeze-Thaw Platforms Defy Cryoconcentration

Freezing and Thawing drug substances in both primary packagings, single-use bags and bottles, in one platform is possible with hybrid freezers. Biopharmaceutical manufacturers and CMOs face challenges to prevent the effect of cryoconcentration during freezing, leading to loss of product quality. Tests have shown that hybrid freezer defy cryoconcentration with homogeneous freezing of both single-use bags and bottles.

Daniel Tischler

December 7, 2022

controlling-cryogenic-freezing-liquid-nitrogen

Freeze & Thaw

Controlling cryogenic freezing with liquid nitrogen

To control cryogenic freezing is not an easy task, especially when liquid nitrogen is involved. To keep small molecules chemically stable and prevent chemical degradation, the right practices have to be in place. Find out everything about controlled cryogenic freezing with LN2 in this article!

Daniel Tischler

November 8, 2022

Drug Delivery

Viral vectors for gene therapy: What to expect in 2023

Viral vectors are looking ahead a bright future in gene therapies. In this article, we give you an overview of the most frequently used viral vectors and have a glimpse at their possible future applications.

Daniel Tischler

October 11, 2022

Bioprocessing

Cryogenic Freezing: All you need to know

Cryopreservation is an effective procedure for the quality-preserving storage of many biomaterials. Find out what cryopreservation actually is, what has to be considered along the process and where it is applied – all summed up in this article.

Daniel Tischler

August 1, 2022

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