APPLICATIONS BY MODALITY
Advanced Fluid Management for Biopharma Modalities
By providing modular standards and highly customizable solutions, we support you in writing a new chapter in advanced biopharma modalities: our single-use technologies and sterile consumables come with the flexibility required for fast turnaround times in advanced therapeutic approches for the areas of controlled freezing & thawing, product aliquotation & filtration and all required logistic steps.
Monoclonal Antibodies (mAbs)
Controlled processes play a vital role for monoclonal antibodies (mAbs) manufacturing processes. mAbs require special care and sensitive handling at every step of the development and production, as well as in logistics, so as not to compromise their effectiveness.
Antibody-Drug Conjugates
Bioconjugates represent a rising class of biopharmaceuticals wherein at least one of the reactants is a biomolecule, often an antibody, protein, or oligonucleotide. The most famous example is the class of antibody-drug conjugates (ADCs).
Advanced Fluid Management for Cell and Gene Therapies
Cell Therapies
Fluid Management Solutions around Single-Use Technologies for Cell Therapies Applications | Autologous Cell Therapy | Allogeneic Cell Therapy
Gene Therapies
Fluid Management Solutions around Single-Use Technologies for Gene Therapies |Primary Packaging | Fill & Drain | Freeze & Thaw | Transport | Gene therapy solutions
Advanced Fluid Management for Viral Vectors & Plasmid DNA (pDNA)
Viral Vectors
With the discovery of new fields of application for viral vectors in gene therapy comes an increased need for dedicated solutions along their supply chain
Plasmid DNA (pDNA)
Plasmid DNA (pDNA) is used as a starting material for the production of mRNA, most commonly known in the context of COVID-19 vaccines. In addition, pDNA is used at the staring point of producing viral vectors, such as AAVs (Adeno-Associated Virus Vectors) and Lentiviral Vectors.
Advanced Fluid Management for mRNA and Vaccines
Messenger RNA (mRNA)
Temperature plays a key role in the Messenger RNA (mRNA) supply chain, as single doses biotherapeutics or vaccines must be kept at temperatures similar to those used in their clinical trials: -70°C (-94°F).
Vaccines
Single-Use Technolgies offer the best advantages to guarantee the needs in today's vaccine production. Due to the highly flexible and scalable nature of single-use components they cover the entire biopharmaceutical manufacturing process, including upstream, downstream, fill-finish and the gaps in-between.