Case Study: Reducing product loss | Hybrid for primary packaging

Claus Exenberger - Single Use Support

Claus Exenberger

July 28, 2022

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CMO and CDMO are forced to collect a series of platform systems for biomanufacturing in different primary packagings: single-use bags, bottles and vials. The handling of different primary packagings results in a lack of standardized process solutions along with varying rates of product loss and inconsistent freezing behavior. To improve process inefficiency there is a need for hybrid platform solutions to cover fluid management for all primary packagings. 

A CDMO, developing and manufacturing drug products for different customers, has decided to to implement a harmonized process solution that can be used with different types of single-use primary packaging whilst at the same time minimzing the rate of product loss.

This case study illustrates the advantages in terms of cost-efficiency and reduced workforce through hybrid systems for protective single-use shell solutions around liquid transfers in biopharmaceutical manufacturing. 

Case Study RoSS - reducing product loss Hybrid for primary packagings

Case Study - Reducing Product Loss | Hybrid for primary packaging

Offering a wide spectrum of biopharmaceutical manufacturing, a customer - a global manufacturing organization - transfers liquids in all common types of primary packagings: Single-use bags: Single-use bioprocess containers that are available in different sizes ranging from 10 mL to 50 L as well as from different suppliers are the primary packaging for drug substance handling, trending throughout the industry. Vials: Ideal for small yet highly valuable amounts of liquids. Sizes vary from 2R to 20R. Bottles: Rigid containers are commonly used in pharmaceutical logistics, the reason for which can mainly be traced back to low costs. Filling volume per bottle ranges from few mL to 10 L
Claus Exenberger - Single Use Support

Claus Exenberger

Product Line Management

Claus Exenberger is Product Line Manager at Single Use Support. As product owner of the RoSS shell, the secondary packaging of single-use bags, Claus and his team develops further non-sterile products to advance handling of single-use bags for the biopharmaceutical industry. With his working experience of 5+ years at Single Use Support he is expert in the protection of all available single-use bioprocess containers. His proximity to customers helps connect his process-oriented approach with the technical development of products.

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