IRIS Single-Use Assemblies | Fluid transfer tubings

Single-use manifold assemblies are assembled single-use components that ensure a sterilized fluid flow of pharmaceutical products. The supply of customized composition of tubings, connectors, fittings, primary packagings, beta bags, filters, etc. and sterilization is usually delayed due to bottlenecks in biopharmaceutical manufacturing. 

As an expert in single-use solutions, we have made it our goal to deliver vendor agnostic single-use assemblies manufactured with highest quality standards in ISO 7 cleanrooms and sterilized within shortest lead time. Prevent downtime and ensure an uninterrupted supply chain in compliance with GMP and regulatory requirements with our single-use systems using silicone tubing.

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100% Customizable


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Single-Use Assembly Catalogue

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Configure your custom single-use assemblies according to individual needs and requirements in the field of aseptic filling. With the online configurator, you can quickly and easily create and order your manifold assembly. 

All our single-use components comply with any FDA, ISO and other regulatory standards and guarantee aseptic handling of your matter. After all, you want to avoid leachables, extractables or any kind of cross-contamination to impact your product before it reaches the end user.

In case of issues or questions regarding configuration, our manifold experts will assist you if there are any issues. You have the option to improve and edit your saved single-use assembly until it meets all your requirements.


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Filter Single-Use Assemblies


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Choose from a wide range of standardized single-use tubing and manifold assemblies for your fluid transfer processes in biopharma processes.

Our customers trust in us:

Rentschler Biopharma SE



Fast delivery of single-use assemblies

The aim is an uninterrupted supply chain and fast delivery worldwide. This is why we guarantee delivery of your single-use assemblies or single-use filtration assemblies and components within shortest lead times. Our clean room manufacturing capacities make our assembly and packaging process faster than the norm, which is why you can rest assured that your single-use tubing assemblies will arrive shortly after you have placed your order (subject to change depending on complexity).

Features and benefits of our fluid transfer tubings

You have the choice of putting together your single-use manifold assembly using the online configurator. Alternatively, you may select a preset designed by our experts and receive additional advice on it. In both events, our manifolds are double-fixed with ties and gamma irradiated  or optionally e-beam sterilized. Thus, a simple connection is possible that meets FDA and ISO regulatory requirements, as well as the highest quality and safety standards for your aseptic filling purposes. 

  • Safe and efficient aseptic filling due to 100% customization
  • Full flexibility due to manufacturer-independent use of materials
  • Easy online configuration of your single-use manifold assembly 
  • Easy connection and disconnection with ties and quick-release couplings
  • Single-Use Consumable Stocking Program available

Our single-use manifold experts are ready to assist you with their knowledge at any time.

Single-use filling assemblies

Podcast Interview: Sustainable trend towards single-use systems

Speed-to-market, flexibility and process efficiency are more important than ever in biopharmaceutical production. And so is the importance of single-use systems. And yet there is hesitation. Dr. Lorenzo De Benedictis provides insights and outlook on the future of single-use systems in Biopharma.


Go with The Flow: How Sustainable is the Trend Toward Single-use Systems?

Filesize: 0.39 MB – Mime-Type: application/pdf

Data sheets

Click here to download technical product data sheets, design videos, as well as case studies and more.

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Datasheet Single-Use Assemblies

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Case Study - Customized IRIS Single Use Assemblies

Case Study - Customized Manifolds

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Single Use Support Manifold Capabilities

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Infografic - single-use assemblies mAb

Infographic: Single-Use Assemblies in Biopharma Manufacturing

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Click here to download technical product data sheets, design videos, as well as case studies and more.

RoSS.FILL - single use filling system for drug substances

RoSS.FILL | Fill-Filtration

RoSS.FILL is a fully automated single-use bag filling system. This allows maximum flexibility and scalability of both the filling and draining process. It is possible to fill unlimited volumes per batch with a speed of up to 300 liters per hour. The entire filling process is fully disposable, thus warranting an absolutely sterile fill & drain process. For further productivity improvements check out our pinch valve innovation.

More solutions

Click here to download technical product data sheets, design videos, as well as case studies and more.

Single use bag protection for drug substances in bulk stream with RoSS shell by Single Use Support

RoSS® Shell | Protecting single-use bags

The safest transport solution for all available single-use bioprocess containers. Robust. Scalable. Single-use bag independent.

Bag Independent
< 0.001 % Product Loss
Best Freezing Results

IRIS Single-Use Bioprocess Container

Innovative. Robust. Individual. Single-Use. Make sure your supply chain is uninterrupted. Get your IRIS 2D single-use bioprocess container from Single Use Support in any size with the fastest possible delivery times. Store and ship anything from cell culture samples to large drug substance volumes reliably and on time.

RoSS.FILL Bag - single use bag filling and draining system machine

RoSS.FILL Bag | Single-use aseptic fill-filtration system for bags

RoSS.FILL Bag is a flexible automated single-use aseptic bag filling machine for dispensing biopharmaceuticals into single-use bags. The fluid path is designed to be fully disposable and is able to accommodate a variety of sterile connection and disconnection options.


RoSS.pFTU Large-Scale | Plate Freeze & Thaw

Up to 400L: Our large scale freezing platform system is a plate-based pharmaceutical freeze and thaw unit. The system enables controlled rate freezing and is compatible with single-use bags of all sizes and manufacturers.

Down to -80°C / -112°F
Up to 400L
Controlled rate freezing & thawing

RoSS.FRDG | Ultra Cold Storage Freezer

RoSS.FRDG is an ultra cold storage fridge for frozen drug substances in different sizes. The ultra cold freezer keeps the desired set point temperature down to -75°C. RoSS.FRDG offers highest storage density, is fully movable and can be modularly adapted to your individual needs.

Single Use Support shipper

RoSS.SHIP | Ship, Track & Trace

RoSS.SHIP secures the cold chain shipping and storing of bulk drug substance for almost one week. Highly robust, stackable, coolable and compact – Fort Knox for high-quality substances!

FAQ about single-use assemblies

What is a single-use assembly?

A single-use assembly is a custom-made component for processing various goods, such as biologics or other products, that need to be kept germ-free. 

Single-use assemblies are often made out of plastic and make sure that workflows are seamless and safe during production and processing, e.g. single-use filtration assemblies.

One great advantage of single-use assemblies is that they are sterile when firstly (and lastly) used and do not need to be cleaned for any additional use, which is both cost- and risk-minimizing.

What is single-use tubing?

Single-use tubing are components used in fluid management of biologics; often made out of plastic, these fluid transfer tubing are necessary when processing various liquids that need to be kept germ-free.

When put into place, single-use tubing is pre-sterilized (typically sterilized by radiation or e-beam sterilized) to avoid contamination along the entire fluid transfer process.

Since they are single-use products, cleaning and sterilization after their application is not necessary, which is both cost-saving and risk-minimizing.

What validation guidelines are in place at Single Use Support manifolds?

​​All single-use assemblies are sterile and in compliance with cGMP production regulatory standards. They are delivered within sterile packaging.

What are the lead times for single-use assemblies from Single Use Support?

We offer lead times of 4-6 weeks after design approval and PO for our custom single-use tubing assemblies.

What single-use components can be purchased via Single Use Support?

Anything you require can be included in your single-use manifold assembly. Be it equipment for filtration, clamps, gaskets, beta bags and stainless-steel protective shells for cell culture media, or other components based on single-use technology.

Are single-use filtration assemblies from Single Use Support compatible with other manufacturers?

IRIS Single-use filtration assemblies offer full flexibility since they are manufactuerer-independent. The filtration assemblies are easy to use with our RoSS.Fill platform system or any other platform from other suppliers. 

More information

IRIS Manifold | Single-Use Assemblies

Single-use systems triage, ultimately affecting the patient

The current shortage of single-use consumables in the pharmaceutical industry has led some experts to go as far as calling it a “triage”: This only makes apparent the immensity and severity of the current challenges in the supply chain, which has far-reaching consequences if not addressed properly.


Johannes Kirchmair

February 9, 2022

Single-use Consumables

Sterile medical filters – Overview of the most reliable producers and their products

An overview of manufacturers and its brands of sterile medical membrane filters for biopharmaceutical fluid management.


Brian Moloney

December 28, 2021

Single-use Consumables

Medical tubing – Manufacturers, types and materials

An overview of manufacturers and its brands of single-use tubings for biopharmaceutical fluid management.


David Seifert

December 27, 2021

Single-use Consumables

Sterile Connectors for use in Pharma

An overview of manufacturers and its brands of sterile and aseptic connectors for biopharmaceutical fluid management.


Brian Moloney

December 27, 2021

Single-use Consumables

Protecting single-use bags to foster their progress

Single-use systems are on the rise. And yet there is hesitation to make single-use technologies continue to thrive. Get to know how single-use systems get full acceptance. 


Michael Eder

November 29, 2021

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