BRMO

Brian Moloney

Director Key Account Management

Brian Moloney is Director Key Account Management at Single Use Support. With this role he is responsible for leading and enhancing strategic client relationships and driving customer satisfaction by aligning our products with client needs. Based on his extensive expertise as service, product and project manager at GE Power, Brian is now market expert in pharmaceutical fluid management. He has joined Single Use Support in 2021.

Find articles from Brian Moloney on Medium: https://medium.com/@brian-moloney

Articles written by Brian Moloney

Drug Delivery

Lipid nanoparticle (LNP) manufacturing: Challenges & Solutions

Being promising tools in life sciences and medicine, lipid nanoparticles are drawing attention on their manifold advantages. In this article, however, we take a step back and discover how LNPs are produced. Solutions based on single-use systems for increasing quality and efficiency in production are also covered. 

BRMO

Brian Moloney

June 21, 2023

Bioconjugates

Transport & Storage of Antibody Drug Conjugates (ADCs)

ADCs can be described as a new rising star among biopharmaceutics. They are able to specifically target and destroy cancer cells very effectively. Their levels of toxicity can vary depending on several factors, including their specific design and the potency of the cytotoxic drug. This is why safe handling in between facilities is such an important issue and must not be taken lightly.

BRMO

Brian Moloney

May 9, 2023

Bioconjugates

Examples of Antibody-drug conjugates

Depending on their constituents, ADCs are extremely variable and can be used for several, very distinct purposes. In this article, we will present you 5 examples of ADCs and their respective characteristics.

BRMO

Brian Moloney

April 25, 2023

Bioconjugates

7 Must-Known Facts About Antibody-Drug Conjugates (ADCs)

Antibody drug conjugates (ADCs) are a rapidly growing field of interest in biopharmaceutics. In comparison to conventional chemotherapy treatments, ADCs have the potential to destroy cancerous cells without damaging healthy cells in the process. In this article we will give you an introduction to this important and rapidly growing field. 

BRMO

Brian Moloney

April 24, 2023

Bioconjugates

Safe Filling & Aliquoting of Antibody Drug Conjugates (ADCs)

The safe handling of ADCs or other HPAPIs is a complex and elaborate process that requires specialized facilities and a safe, sterile environment. The filling/aliquoting step in particular calls for great care and specific equipment to ensure sterility and rule out any potential cross-contamination as well as potential harm to handling staff.

BRMO

Brian Moloney

April 24, 2023

Bioconjugates

Bioconjugates manufacturing & the advances with single-use technology

The manufacturing of bioconjugates is a complex process that involves linking a drug payload with a targeting moiety using a linker. The process is highly specific and requires careful optimization to ensure that the bioconjugate is effective and safe for use in patients. Single-use technology has revolutionized the manufacturing of bioconjugates by offering a range of benefits over traditional stainless-steel manufacturing. Therefore, this article will pay special attention to this subject. 

BRMO

Brian Moloney

April 24, 2023

Bioconjugates

ADC manufacturing: Process, Challenges & Solutions

Scale-up and industrial production of ADCs face complications due to the high safety measures which need to be taken to guarantee product efficacy and a protected working environment for staff and manufacturers. In this article we seek out to give you an overview of the different challenges during ADC manufacturing while also introducing solutions which help to ensure aseptic production methods through single-use-technologies and end-to-end systems. 

BRMO

Brian Moloney

May 5, 2024

Bioprocessing

Simplifying Cryopreservation of Cell Monolayers

Advanced cell-based assay workflow with CryoLogyx Thaw and Test pre-plated cell and controlled, scalable freezing process solution RoSS.pFTU to achieve effective cryopreservation of cells.

BRMO

Brian Moloney

August 9, 2022

Cell & Gene Therapy

Autologous vs. Allogeneic Cell Therapy

Although autologous and allogeneic cell therapies share both defining methodological key elements as well as various fields of application, including most innovative cancer therapies, there are significant differences between them. Therefore, a closer look on both procedures shall be presented.

BRMO

Brian Moloney

May 18, 2022

Fill & Filtration

How to safely connect a single-use tubing set?

When safety, time and flexibility are of the essence, the solution should be an easy one. This is why the team at MyManifold have come up with an intuitive, easy-to-use configurator for sterile filling systems. Users can design their own assembly prototype. Read how!

BRMO

Brian Moloney

January 3, 2022

Fill & Filtration

Aseptic bag filling – 5 critical considerations

Aseptic bag filling is a process that is very important to the biopharma industry. This article will give you the basics of aseptic bag filling, highlight the most critical factors of the technique and discuss key considerations pertaining to the commercial use of aseptic bags.

BRMO

Brian Moloney

March 2, 2022

Cell & Gene Therapy

Supply chain optimization in cell and gene therapies

Single Use Support is solving problems related to supply chain management through the development of smart packaging and related smart technologies for CAR T-cell therapy. Read more!

BRMO

Brian Moloney

December 20, 2021

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