Michael Mühlegger

Vaccine manufacturing is an ever-evolving area. In this Article, we will cover some novel approaches that biopharma increasingly relies on.

Liquid handling is one of the cornerstones in countless biopharmaceutical manufacturing processes. In this article, we will illustrate how automated systems can improve efficiency – along with several other aspects.

What are the necessary considerations when implementing automated fluid management systems in biopharma? In this article, we will discuss seven of the most important ones.

Bioprocess manufacturing has seen remarkable advancements through the utilization of single-use technology. This shift in process development brings numerous advantages – in this article, we will cover some major advances.

There are several differences, but also a few significant similarities between viral vector vaccines and non-viral-vector based mRNA vaccines – we will uncover them in this article.

Viral vectors have become an indispensable tools in therapeutic and research applications. In this article, we will provide a broad overview of this fascinating topic.

In this blog post, we'll show examples of AAVs as gene therapy vectors and examine the tangible results of FDA-approved AAV gene therapies, which offer actual solutions and hope for patients affected by genetic disorders. 

The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA.

Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, the applications, unique attributes, and the complex terrain of producing viral vectors.

The pDNA manufacturing process is multifaceted yet essential in the biopharmaceutical industry. Here, we will describe the process step by step.

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.

Plasmids are part of the genetic material in bacteria, complementing chromosomal DNA with additional functions. But there is much more to plasmids, as you can read in this article.