RoSS.pFTU lab scale/ FREEZE & THAW

Compact freeze & thaw unit for cell cultures in small batches.


Monitored freezing and thawing of small batches – more important than ever in Seed Train Intensification in Upstream!

Our experience with BULK.STREAM® – as well as from developing our compact freeze & thaw facilities for labs and research institutions – forms the basis for the RoSS.pFTU lab scale system. RoSS.pFTU lab scale is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process, and is also best suitable during High Cell Density Cryopreservation.

Another milestone towards more patient safety in upstream through:

  • Controlled quick freezing
  • Scalable freezing of high volumes in upstream
  • High cell viability after freezing



  • Benchtop lab scale freeze and thaw platform
  • Compatible with single use bags of all manufacturers
  • Lab scale freezes drug substance volume from 1 ml to 5 l per bag
  • RoSS shell and RoSS.KSET can be used for freezing
  • Freezing at highest possible speed & accuracy
  • Ensures best product stability results

Scale-up solutions from Lab Scale to Blockbuster Scale!

3 liters / pre-clinical or Phase 1/2

150 liters / Phase 2/3 or commercialized

300 liters / commercialized

We tried to visualize Cryoconcentration by using Naphthol Blue Black as color agent. An in- tense blue coloration shows a high concentration of dissolved solutions. The bags frozen in the plate freezer exhibit a homogenous tinge with a white line running through the center. The bag frozen in the static freezer exhibits higher concentration levels in the lower areas.

blast freezer
“slow freezing”

Dark blue spots indicate a higher croyconcentration.

plate freezer
“fast freezing”

Bei einem homogenen Gefrierbild sind keine dunkelblauen Flecken sichtbar.


We see issues with integrity of Single Use Systems in the biopharma world. Potentially, the MITS.2D technology is able to help address Endotoxin and Bioburden issues properly. Sterility is key for some applications very close to the patient in Fill and Finish facilities. Midterm, MITS.2D might be able to mitigate the risk of biocontamination in these process steps also.


FDA authority, USA

We were looking for a solid shipping solution for our single use bags. None of the available solutions to date offered reassuring solutions.
Thanks to a fortunate coincidence we got in touch with SUSupport. Not only have we found a more than solid solution for our main problem thanks to their product RoSS® but we now have access to a clever and 100% safe drug substance logistics system.

Program Manager

Lonza AG, Basel

We were analyzing different solutions on the market for freezing and thawing our drug substances in single-use bags.
The combination of a bag agnostic robust secondary packaging RoSS and the scalable plate based freeze/thaw technologies convinced us to select Single Use Support.
It not only matches all our requirements, it is also safe, easy to navigate and flexible to single-use bags from any supplier.
Furthermore, it is a good starting point to expand to a whole end-to-end solution.

Program Manager

3S Bio

Click here to download technical product datasheets.