Storage Density in Biopharma Manufacturing Facilities

micheal-eder

Michael Eder

March 24, 2022

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Especially manufacturing plants with high commercial production of biopharmaceuticals face limitations in storage space.

Single-use bags with its flat shape is predestined for stacking and offer great solutions to increase storage density on-site but also for shipment.

The combination of both, single use bag and RoSS® shells (Robust Storage and Shipping) makes them a cost-effective solution, as they require little storage space. RoSS® shells are available for all sizes and suppliers of single-use bags.

Avoiding product loss by single-use-bag protection

Comparing single use bags to PE bottles, the cold room storage density with single-use bags is almost 4 times higher.

For example, 5L bottles can be stored at a density of about 80L/m3 whereas single-use bags offer a density of approx. 330L/m3, which leads to significant cost savings and future growth without having to invest heavily in cold room storage capacities.

Higher storage density
thomas-wurm

The rectangular design of RoSS® enables huge optimization for Biopharma companies in terms of storage density, irrespective of what single use bag is inside.

Thomas Wurm, CEO

Long term ultra cold storage

The dependence on blast & static freezers for storage and cooled storage rooms and the subsequent limitations due to incompatibility to RoSS shell dimensions has proven that there is room for optimization - ultra cold fridge for lab

RoSS.FRDG, the cold storage end-to-end platform, helps to maximize the storage density of RoSS® shells as it is compatible to all RoSS® shells and sizes on the market.

RoSS.FRDG offers not only a great relief for storage capacities due to its high storage density and stackability of RoSS® shells, but is also another way out from incompatibilities of technologies due to its tailored design. It enables a seamless transition between deep-freezing (RoSS.pFTU) and shipping (RoSS.SHIP) or thawing in an end-to-end process with a high degree of flexibility in-plant due to its portable use.

Ultra cold storage freezer - RoSS.FRIG high density

Shipping

The advantages in storage space when using RoSS® also facilitate shipping. As frozen single-use bags could not be safely stacked without a robust secondary packaging without risking breakages and severe product losses, RoSS® offers better solutions for in-plant storage, in-plant transportation, and international shipping

Previously, it took one pallet to transport 2 bags. After the introduction of RoSS.SHIP, 10 bags – 120 liters of BDS (bulk drug substance) – could be filled into one pallet. This is a reduction of storage space during transportation by 80%. Consequently, the increased storage density not only had an impact on the storage space, but also on the volume of freight in trucks and airplanes and less labor hours through more efficient handling of the deliverable.

Load per pallet

Case Study - RoSS Shell Storage Density

Single-use bags have been selected as the primary package and the RoSS® shell (Robust Storage and Shipping) (Figure 2 & 3) as the robust secondary packaging solution for the single-use bags. The combination of both, single-use bag and RoSS® shell, makes them a cost-effective solution, as they require little storage space and minimizes product loss to > 0.001 %. RoSS® shells are available for all sizes and suppliers of single-use bags.

More information

RoSS.FRDG_Cold Storage of Biopharmaceuticals

Best choice for cold storage of Biopharmaceuticals - A Comparison

What's the best choice for long-term cold storage of valuable drug substance? Comparing different Biopharma technologies.

RoSS controlled handling of drug substance

Frozen Storage and Shipping in biopharma with RoSS

Single Use Suppport’s RoSS (robust storage and shipping) shell, composed of an outer sleeve of robust stainless-steel and an adaptive inner layer of 3D foam, contributes to a safe journey. It warrants the single-use bag’s intact arrival at its final destination, keeping its precious contents protected from biocontamination and other damages. 

Single Use Support shipper

Case Study: How to save storage space with single use bags

Only the combination of single use bags and RoSS shells increased the storage density due to its rectangular geometry and its possibility to stack. Learn more – [including podcast episodes]
 

micheal-eder

Michael Eder

Senior Marketing Manager

Michael Eder, MA, is Senior Marketing Manager at Single Use Support. He is expert in pharma and health communication with his 8+ years experience in pharma. After completing his master's degree in International Healthcare Management at MCI The Entrepreneurial school in Innsbruck, he has gained experience in the pharmaceutical field. Michael creates articles about Freeze Thaw applications and Platform solutions from Single Use Support and is the author of current news with Single Use Support worldwide. 

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