Freezing & Storing biopharmaceuticals at -80°C and below - The best economical choice

Alexander Fuchs | Single Use Support

Alexander Fuchs

January 19, 2021

Table of contents

Show

Overview

There are many choices on how to freeze your biopharmaceutical bulk material. Some freezing methods focus on deep freezing while others long-term storage to hold temperature. But what is the most effective and efficient approach for my cold chain?

Controlled rate freezing via plate freezers have scientifically proven advantages over conventional blast/static freezers; yet the latter remain on the market because they have perceived advantages like low capital cost, easy installation, and appear easy to use.

In this publication we show that the intital price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecylcle analysis they outpace conventional options regarding total costs.

Whitepaper: Freezing & Storage of Biopharmaceuticals at -80°C

In this publication we show that the initial price can be deceiving and there are significant additional costs during ongoing usage in the long term. Plate freezers ensure a complete, consistent, and fast freezing (and thawing) to ensure the quality of your high-valued drug substance is maintained, and through simple lifecycle analysis they outpace conventional options regarding total costs.
Alexander Fuchs | Single Use Support

Alexander Fuchs

Head of Product Line Management

Alexander is Head of Product Line Management. He owns a wide range of experience and knowledge in various and different industries such as jewellery, manufacturing industry and biopharma, and multiple areas of activities due to his highly technical education and intensive insights. 

Passionate for Automation, Engineering and Process Management Alexander contributes to the innovative focus of advancing cold chain management within the biopharmaceutical industry. 

More from Alexander Fuchs

Vaccines

Freeze thaw processes in biosimilar production

Freezing and thawing are essential steps in the cold chain management of biosimilars. With several methods eligible, we have chosen some prominent ones, explaining their advantages, limitations, and our preferred choices.

Alexander Fuchs | Single Use Support

Alexander Fuchs

May 8, 2024

Vaccines

Safe storage of biologics: Requirements & solutions

Once biologics are produced, they need to be stored for shorter or longer periods of time, with dedicated storage requirements to be met. Here, we will uncover these requirements, along with solutions to fulfill them.

Alexander Fuchs | Single Use Support

Alexander Fuchs

May 8, 2024

Read more about Freeze & Thaw

Vaccines

Safe storage of biologics: Requirements & solutions

Once biologics are produced, they need to be stored for shorter or longer periods of time, with dedicated storage requirements to be met. Here, we will uncover these requirements, along with solutions to fulfill them.

Alexander Fuchs | Single Use Support

Alexander Fuchs

May 8, 2024

End-to-end Solution

Protein storage: How to increase protein stability?

Prior to be used in diagnostics or therapeutics, proteins have to be safely stored. In this article, we will assess methods to preserve their stability upon storage.

Alexander Fuchs | Single Use Support

Alexander Fuchs

April 10, 2024

End-to-end Solution

Protein stability – all you need to know

Protein stability is crucial to be maintained along the manufacturing process of protein-based products. In this article, we will discover what influences protein stability, along with methods to assess and increase it.

Khalil Essani - Single Use Support

Khalil Essani

April 9, 2024

Freeze & Thaw

Cold Storage Requirements for Active Pharmaceutical Ingredients

Active pharmaceutical ingredients (APIs) are fundamental for drug products to be effective, but require special treatment – e.g. considering humidity, light, or temperature. In this article, we will highlight the different cold storage requirements of APIs, including examples and an overview of different practical approaches.

Alexander Fuchs | Single Use Support

Alexander Fuchs

March 21, 2024