ROSS.KSET | Protecting small single-use bags

Scale-down to one single drop of drug substance!

RoSS.KSET offers the protection for drug substances with volumes less than 250 mL. The shell is robust, closed, safe and sterile – most suitable for cell and gene therapies or clinical studies.

For larger volumes, RoSS can protect one or multiple single-use bags in one shell.

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Fast lead times

Delivery within few weeks

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Worldwide shipping

We deliver all over the globe

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Our customers trust in us:

3SBio Inc.

The combination of a bag agnostic robust secondary packaging (RoSS®) and the scalable plate based freeze/thaw technologies convinced us to select Single Use Support. It not only matches all our requirements, it is also safe, easy to navigate and flexible to single use bags from any supplier.

Lonza

Thanks to a fortunate coincidence, we got in touch with Single Use Support. Not only have we found a more than solid single-use solution for our main problem thanks to their product RoSS®, but we now have access to a clever and 100% safe drug substance logistics system.

Genezen

Having partners such as Single Use Support in place will be one of many essential components as we scale our operations to deliver high-quality programs and vector production services to our clients.

100% Protection

The equivalent of RoSS for small scales – hard, manipulation-safe shell!

Scale down to one single drop of drug substance! RoSS.KSET offers the protection for drug substances less than 250 mL.
For anything above, RoSS can protect one or multiple small single use bags in one shell.

In RoSS.KSET, single use bags are covered with one layer of soft 3D foam. This offers protection and dampens shocks. Furthermore it allows for an expansion of the liquid volume and the bag in the freezing process and immobilizes the frozen bag in the hardened foam. An innovative and intuitive sealing system is a further feature to warrant functionality and safety.

The RoSS.KSET unit is made of high-density stainless steel. The container can be locked and tamper-evidence sealed. This guarantees absolute protection against manipulation as well as intuitive handling at the same time.

Advantages of the stainless steel construction:

  1. Stainless steel offers maximum durability and extreme strength.
  2. When in direct extensive contact with the bag, it is the ideal basis to keep the freezing process effective from the beginning all the way to the end and allows for a gentle thawing process.
  3. The stainless steel shell is safe up to temperatures of -200°C / -328°F.
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Facts about the RoSS.KSET:

  • A container for all standard compact 2D single use bags (e.g. Origen, Miltenyi Biotec, …) and all sizes
  • Robust and closed construction, construction, with temperature regulation, to secure the single use bag
  • Viewing window to read captions when container is closed/sealed
  • 3D foam offers extra space and protects the sensible connection of raw bag and tubing – complete immobilization < 0°C / 32°F
  • Space for satellite samples/ID bags/vials
  • Sealable locking system protects against manipulation
  • Suitable for cells (Apheresis), viruses and DP bags
  • L2 DEWAR/Shipper compatible
  • Stainless steel container for consistent and quickest possible freezing and thawing
  • High density, which means compact measurements of the shipping unit
  • Ease of use during the recycling process – no composite materials
  • Robust locking-/opening mechanism with clear indicator
  • Open/locked clearly indicated
  • Easy to lock with thick gloves
  • Special lock to minimize risk of pinching and of damaging the single use bag

Like an amulet, RoSS.KSET carries its content softly covered and protected around the globe.

In case you are searching for a solution that carries one bigger or multiple smaller single use bags, check out the RoSS shell as alternative option for CGT applications.

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RoSS.KSET RACK | Protect & Ship

How can RoSS.KSET RACK protect small scale single use bags?

Highly robust and compact – a CGT (cell & gene therapy) vault for standard shipper systems.

In a first step, we developed a suitable RoSS.KSET based on standard single use bag sizes that, in a second step, can be manufactured according to required capacity needs of the RACK units.

The Rack for RoSS.KSETs has been developed for the safe placement of all standard manufacturers (Cryoport, Savsu, …) in shippers for transport or storage and is able to withstand temperatures up to -200°C / -328°F.

The main construction material is high-density stainless steel. It is compact, lockable, safe to freeze, sealable, and thus protected against manipulation.

Another step towards 0% product loss and thus 100% patient safety!

In case you are searching for racks for drug substance in RoSS shells, check out our RoSS Accessories that can be customized to your needs:

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RoSS® Shell | Protecting single-use bags

The safest transport solution for all available single-use bioprocess containers. Robust. Scalable. Single-use bag independent.

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IRIS Single-Use Bioprocess Container

Innovative. Robust. Individual. Single-Use. Make sure your supply chain is uninterrupted. Get your IRIS 2D single-use bioprocess container from Single Use Support in any size. Store and ship anything from cell culture samples to large drug substance volumes reliably and on time.

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RoSS.SHIP | Ship, Track & Trace

RoSS.SHIP secures the cold chain storage and shipping of bulk drug substance for almost one week. Highly robust, stackable, coolable and compact – Fort Knox for high-quality substances!

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IRIS Single-Use Assemblies

As an expert in single-use solutions, we have made it our goal to deliver single-use assemblies manufactured at highest quality standards in ISO 6 cleanrooms and sterilized within shortest lead times. Prevent downtime and ensure an uninterrupted supply chain.

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Bottle RoSS | Protecting Bottles

RoSS (Robust Storage and Shipping) can also be translated for PE rigid containers. With Bottle RoSS the tubings on bottles are protected at glass-like sub-zero temperatures with the help of a soft 3D foam which hardens at frozen state.

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RoSS.FILL is a flexible automated single-use technology for dispensing biopharmaceuticals into single-use bags. The fluid path is designed to be fully disposable and is able to accommodate a variety of sterile connection and disconnection options.

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RoSS.pFTU Lab-Scale | Freeze-Thaw

Laboratory freezer, compatible with single use bags of all sizes and manufacturers. Our lab freezer is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process.

FAQ

Should I fill the biocontainer inside the shell or outside the shell?

Yes, both options are possible. Either fill the bag and place it in the RoSS® System or place the empty bag in the system and fill it with a fully automated filling system, compact and with little air. Learn more about RoSS.FILL.

How does a CCU (Cryo Control Unit) work?

We developed a system called Cryo Control Unit (CCU) which is an insolation material styro foam piece that covers the shoulders of the single-use bioprocess container and the shell. CCU is meant for enabling the use of RoSS® shells in standard lab freezers or in blast freezers.

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