Ultra Cold Storage Freezer | RoSS.FRDG

Frozen storage down to -75°C

RoSS.FRDG is an upright ultra-cold storage freezer for frozen drug substances in different sizes. The fridge for laboratories keeps the desired set point temperature down to -75°C. 

Our ultra-cold freezer is compatible with RoSS Shells to protect your bioprocess containers. It offers highest storage density, is fully movable and can be modularly adapted to your individual needs.

Ultra-cold storage RoSS.FRDG

Fast lead times

Worldwide shipping

Personal customer service

Advantages of the high density ultra cold freezer

  • Great relief for ultra cold room storage capacities due to its high storage density and stackability of RoSS shells
  • Seamless transitions between deep-freezing (RoSS.pFTU) and shipping (RoSS.SHIP) or thawing in an end-to-end process
  • High degree of flexibility in-plant due to its portable use
  • strong helping hand in-plant to prevent staff from carrying heavy loads manually
  • Another way out from incompatibilities of technologies due to its tailored design

Facts on the ultra cold storage RoSS.FRDG

  • Insulated container for long-term cooling of drug substances in RoSS Shells
  • Upright Freezer Style
  • Ultra-cold Freezer: Holds desired temperature down to -75°C
  • Ease of use for loading: place loaded Trolleys or Racks as a whole inside
  • Fully modular: customized shelving systems
  • GMP compliant alarm management
  • Temperature monitoring
  • Flexible storage location
  • Compatibility to RoSS single-use technologies
  • Contains up to 300L of drug substance
  • Powered by natural gases
  • Choose between water- or air-cooled system
Ultra cold storage freezer - RoSS.FRIG high density

As a modular and efficient Ultra Low Temperature (ULT) freezer, it is the perfect solution for all requirements. It outperforms both, conventional upright laboratory freezers and walk-in freezers and cold rooms thanks to its advantages for all biomanufacturing companies; full temperature control thanks to reliable air temperature conformity and a highly modular interior that can be equipped with shelving systems to store all available single-use bags and bottles.

Simply place pallets into RoSS.FRDG - without changing the regulation-intensive infrastructures. Thus RoSS.FRDG enables modular and easy-to-install cold room storage capacity that smartly fills a gap for the biopharmaceutical industry between small-scale low storage density lab freezers and large but expensive and fixed walk-in freezers.

RoSS.FRDG_Comparison_Missing Link_Puzzle

Advantages of RoSS.FRDG to other solutions in the industry


Conventional Lab Freezer

RoSS.FRDG Ultra Cold Storage

Walk-in Freezer & Cold Room


Temperature Control


Reliable Air Temp Uniformity of 1.5°C and wide-ranging setpoints with RoSS.FRDG

Storage Density


Pallets, racks and other packagings in shelves to be stored efficiently


Customized shelving systems for sizes of primary packagings

Cost effectiveness

Simple installation and maintenance of RoSS.FRDG without change of infrastructure 

Back-up plan

Digital alarming management and long holding of temperature in case of failure

Our customers trust in us:

Rentschler Biopharma SE



Fridge for labs meets all requirements

The ultra cold storage freezer RoSS.FRDG is designed to meet the requirements of a fridge for labs: the laboratory fridge allows highest temperature stability down to -75°C, and is compatible with RoSS Shells to provide maximum protection for single-use bags.

In addition to its high flexibility, this lab fridge comes with great storage space, easy access and is stackable; also, RoSS.FRDG is scalable and therefore suitable to deliver enough space both as a fridge for labs and in bulk production and storage of biopharmaceuticals.

Manual defrost is not necessary to keep the freezer storage within the RoSS.FRDG frost-free, and with the temperature alarm, stainless steel surfaces, adjustable temperature down to -75° C and precise temperature control, this device delivers freezer space that is ready to meet both lab requirements and international regulations.



Integrate into your cold chain process

As part of the Freeze & Thaw platform by Single Use Support, RoSS.FRDG is a device ready to be integrated in highly delicate cold chains. This platform allows seamless transitions from the unfrozen to the frozen and back to the unfrozen state of biologics: Together with the RoSS.pFTU – a powerful freeze/thaw unit that comes in different sizes –, it enriches Single Use Support’s Portfolio of professional end-to-end solutions.

In order to provide even more efficiency, safety and user-friendliness within the freeze/thaw process, Single Use Support additionally provides various consumables, such as RoSS Shell. The product is designed to protect single-use bioprocess containers during storage and transport and is compatible with the Freeze & Thaw platfrom RoSS.pFTU.

Data sheet


Datasheet RoSS.FRDG

Filesize: 0.3 MB – Mime-Type: application/pdf

Whitepaper RoSS.FRDG_Maintaining ultra low temperatures

Whitepaper: RoSS.FRDG Cold Chain at Ultra-Low Temperatures

Filesize: 1.58 MB – Mime-Type: application/pdf

Case Study_RoSS.FRDG_Universal Ultra Cold Storage

Case Study - Universal Ultra Cold Storage

Filesize: 0.34 MB – Mime-Type: application/pdf

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Laboratory freezer RoSS.PFTU Lab Scale

RoSS.pFTU Lab-Scale | Plate Freeze & Thaw

1mL-10L: Laboratory freezer, compatible with single use bags of all sizes and manufacturers. Our lab freezer is the perfect solution for studies conducted in labs and, above all, if you want to start a controlled and scalable freezing process.


RoSS.pFTU Mid-Scale | Plate Freeze & Thaw

Up to 100L: Our mid scale freezer is a plate freezer and thaw unit designed for RoSS shells, to protect your preferred single-use bag during cryogenic applications. 

RoSS.pFTU mid scale is compatible with single-use bioprocess containers of all sizes and manufacturers and shows best product stability results for your biopharmaceuticals up to 100L. 


RoSS.pFTU Large-Scale | Plate Freeze & Thaw

Up to 400L: Our large scale freezing platform system is a plate-based pharmaceutical freezer and thaw unit for any scale and batch size. Well-established RoSS.pFTU large scale is compatible with single-use bags of all sizes and manufacturers. The hybrid solution offers freeze-thaw capabilities for bags and bottles up to 400L in one platform.  


ROSS.SHAK | Shaker

RoSS.SHAK is your reliable shaker to regain highest quality and homogeneity of your biopharmaceuticals.

RoSS.SHAK enables constant shaking of your protein to regain homogeneity and product quality after freezing. Shakes up to 70L per run in 3 pre-defined speeds.

Product Photo_RoSS.PADL-1-trim

RoSS.PADL | Homogenizing Solution

RoSS.PADL is a scalable massaging platform for achieving a uniform mixture in
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RoSS.LN2F | Cryogenic Freezer

RoSS.LN2F is a powerful cryogenic controlled rate freezer for temperatures down to -170°C/-274°F. An enclosed LN2 system and our innovative direct injection system ensure no direct exposure and no mechanical compressors are needed. This ensures a safe, low-maintenance and energy-saving handling.

FAQ about ultra cold storage

What are ultra cold freezers?

Ultra cold freezers, also known as ultra low temperature freezers or ULTs, are refrigerated that are designed to achieve temperatures as low as -40 to -86° C. They represent a significant component in the supply chain of various products, including most innovative biologics.

What is the difference between a lab freezer and a fridge for lab?

Both the lab freezer and the fridge for labs work with extremely low temperatures. But while lab freezers are devices that are made to cool down specific goods to these low temperatures, fridges for labs are designed for the storage of the frozen goods in the appropriate temperature range.

Single Use Support has created both the freeze/thaw platform RoSS.pFTU (with high-performance plate freezers in different sizes) and the RoSS.FRDG, which is a specialized freezer for labs that is scalable, stackable, comes with high storage density and great temperature stability.

Who uses the ultra cold freezer RoSS.FRDG?

The ultra cold freezer RoSS.FRDG is used all along the biopharma industry, from laboratories to transport experts and in biopharma companies. Since it offers high storage density and is easily stackable, it is extremely flexible in use and can be integrated in processes from lab to bulk scale.

What is the difference between a household freezer and an ultra cold temperature freezer?

In contrast to the usual household chest freezers or upright freezers with wire baskets that can be found at various retailers including Amazon next to whirlpools and other rather ordinary household products, ultra cold temperature freezers are highly specialized devices far more powerful than fridge-freezers or the extra-freezer on casters. They can reach temperatures that household devices – even the bestselling, best chest freezers – cannot achieve with cold air from an ordinary compressor.

Although ULT freezers might share some typical functions with small chest freezers (like a power-on indicator light that helps to become aware of power outage), ultra low temperature freezers need not only to provide lower, but also more stable temperatures than a compact chest freezer, since it contains far more delicate substances.

More information


Pharmaceutical cold chain management – from cold to ultra-cold: An overview of all freezing ranges

Temperature plays a significant role in the production and distribution of several revolutionary biologics. But how does the pharmaceutical cold chain work, and what temperature ranges are most frequently chosen? You will find out in this article!

Ultra-cold freezing and storing – considerations & solutions

Ultra-cold freezing and storing – considerations & solutions

Implementing cold freezing and storing in supply chains is oftentimes inevitable when dealing with certain biopharmaceuticals. Learn what the main considerations are and find out how to face related challenges.

Single-use technology

Single-use technology & the implementation in biopharma

Single-use technologies, which reduce the risk of cross-contamination of high-quality bulk drug substances, are becoming increasingly popular in the pharmaceutical industry. You can find out the reason for this in the blog post!


Whitepaper: How controlled freezing enables scalability

In a comprehensive study the impact of ice front growth speed on scalability of freezing protein solutions has been evaluated.

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