RoSS.FILL Bottle - single use bottle filling

Aseptic single use bottle filling and filtration system

The fully automated RoSS.FILL aseptic single use bottle filling and filtration system enables worry-free filling and filtration of your liquid drug and non-drug substances into bottles. 

With its high filling accuracy, the platform provides continuous filling for up to 20 bottles at the same time as a closed single use filling system.

Single use bottle filling RoSS.FILL bottle

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Fujifilm Diosynth



AGC Biologics

Features and Benefits of our single use bottle filling machine

The cGMP compliant design of the RoSS.FILL bottle filling and filtration machine allows controlled and automated transfer of your fluids without limitations for your custom process:

  • Continuous filling possible: Up to 20 bottles (up to 5L) get connected to control unit at point of use
  • Hygienic Design: easy to clean surface thanks to improved design 
  • Single-Use Filtration Assembly gets easily placed on the system 
  • TPE Automatic Sealer & Stepper Pinch Valves for filling and venting line
  • 1 Weighing scale per bottle 
  • GMP, CFR Part 11 compliant software control unit can be used with the bottle rack or the bag/shell rack 
  • Hybrid solution for single-use bag filling (see RoSS.FILL) and bottles (with Flex Rack) 
  • Same control unit (just switching rack) 
  • Optional MES integration to DeltaV or other
Single use bottle filling RoSS.FILL bottle

Advanced Sealer & Stepper Pinch Valve

2 functions in 1 device: Variable fluid control for fast filling + simple aseptic decoupling

Automated Sealing Function:

  • Dropless disconnection by sealing
  • No need for cumbersome post processing of metal seals and giving the benefit of removing sharp edges
  • Fully aseptically closed – no risk of leakage
  • Simple Aseptic Decoupling: safer, automated disconnection
  • The fully tested sealed tubings withstand a temperature of up to -190°C

Automated Stepper Function:

  • Closed or open or anywhere in between
  • Run your pump at 100% speed - allow the stepper to control the fill rate
  • Unprecedented levels of control in your fill recipe
  • Fastest filling rate
  • Fill several bottles in parallel
Sealer Valve_3

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Enabling end-to-end process solutions for bottles

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