RoSS.FILL Bottle - Bottle Filling System for Biopharma

The fully automated RoSS.FILL aseptic single use bottle filling and filtration system enables worry-free filling and filtration of your liquid drug and non-drug substances into bottles. 

With its high filling accuracy, the platform provides continuous filling for up to 36 bottles at the same time as a closed single use filling system.

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capacity

Up to 360L+/Batch

highest-accuracy (1)

Highest Accuracy

fast-throughput

Fast Throughput

Our customers trust in us:

Rentschler Biopharma SE

Lonza

SCHOTT Pharma

Features and Benefits of our single use bottle filling machine

The cGMP compliant design of the RoSS.FILL bottle filling and filtration machine allows controlled and automated transfer of your fluids without limitations for your custom process:

  • Suitable for any bottle size up to 10L
  • Flexible setup to optionally attach up to 6 racks per run
  • Parallel filling of up to 3 racks in parallel
  • Ease of use in operation / recipe driven processing
  • Single-Use Filtration Assembly gets easily placed on the system 
  • GMP, CFR Part 11 compliant software control unit can be used with the bottle rack or the bag/shell rack
  • Hiqhest Accuracy with precise scales
  • Hybrid solution for single-use bag filling (see RoSS.FILL) and bottles (with Flex Rack) 
  • Same control unit (just switching rack) 
  • Optional MES integration to DeltaV or other
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Data sheets

Datasheet RoSS.FILL Bottle

Datasheet RoSS.FILL Bottle

Filesize: 0.57 MB – Mime-Type: application/pdf

RoSS.FILL Scale Overview

Scale Overview RoSS.FILL

Filesize: 0.68 MB – Mime-Type: application/pdf

Datasheet_IRIS_Single-Use Assemblies_Single Use Support

Datasheet Single-Use Assemblies

Filesize: 0.68 MB – Mime-Type: application/pdf

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Drain your single use bags at Fill & Finish site. This standalone draining rack enable controlled fluid flow while draining single-use bags. Connected peristaltic pumps enable lowest holdup volume. Multiple racks can be attached for simultaneous and continuous pooling thanks to inclination of all shelves. All disconnection types possible.

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More information

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The fill and drain process for biopharmaceutical products can be a massive challenge for the biopharma industry. Here, single use systems offer a multitude of advantages.

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Autologous therapies and other ATMPs with small volumes exhibit certain specific requirements. The scope of handling advanced therapies require special handling and care. When handling of small volumes is already automated in an early stage, it is a way more straightforward path to commercialization of the drug product. The benefit of a closed systems with automated solutions add value by offering a higher degree of sterility, safety, and process flexibility.

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Aseptic bag filling is a process that is very important to the biopharma industry. This article will give you the basics of aseptic bag filling, highlight the most critical factors of the technique and discuss key considerations pertaining to the commercial use of aseptic bags.

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Enabling end-to-end process solutions for bottles

The Single Use Support end-to-end process for bottles can be applied independently from bottle manufacturer, it is modular and can be topped off with services such as qualifications, after-sales service and biopharma know-how.

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