Enhancing Process Flexibility With Automated Filling

micheal-eder

Michael Eder

March 5, 2024

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Addressing Challenges in Aseptic Filling

Accurate and efficient filling of biopharmaceuticals in primary packagings, such as single-use bags and bottles, is crucial. 

Even the smallest deviations in the filling volume can have a huge impact on the production process, or finally on the patient‘s therapy. For example, if a liquid needs to be frozen for
transport, overfilling or an inconsistent volume of single-use bags seriously increases the risk of bag leakage and product loss. In most cases, it is absolutely important that a patient receives exactly the same volume of the medication per injection. Operational errors in aliquotation processes often occur due to manual intervention or limitations. 

Highest Accuracy: Single Use Support with Sonotec

In order to implement flow sensors with the highest precision, Single Use Support decided to implement SONOTEC's SONOFLOW CO.55 V3.0 ultrasonic flowmeters on its RoSS.FILL platforms for dispensing small volumes. The sensors are simply clamped onto the tubing and measure without contact, thus eliminating the risk of contamination or leakage.

Discover the full benefits of SONOTEC's collaboration with Single Use Support for biopharmaceutical fluid management in the new application note.

App Note: Enhancing Flexibility & Accuracy With Single Use Support and Sonotec

Enhancing Process Flexibility and Filling Accuracy With Automated Filling. For low volume dispensing at a commercial scale, accuracy and repeatability are essential. To achieve a filling accuracy range of even less than ± 1 mL with the RoSS.FILL platform, Single Use Support decided to implement SONOTEC‘s SONOFLOW CO.55 V3.0 ultrasonic flow meters. Hence, RoSS.FILL users benefit from advanced process safety, flexibility, and scalability with accurate and airless volume dosing.

More Information

RoSS.FILL Lab Scale offers unprecedented filling accuracy

Aseptic Filling of Small Volumes with High Precision

Filling accuracy has become increasingly important for laboratories and biopharmaceutical manufacturers. Single Use Support has developed best-in-class filling precision for aliquoting small single-use bags with its RoSS.FILL Lab Scale aseptic filling platform.

RoSS.FILL CGT Small Volumne_Product Photo-3-min

Revolutionizing Commercial Aliquotation in Cell and Gene Therapies

Single Use Support unveils its latest customized innovation within the product range of automated of biopharmaceutical manufacturing, RoSS.FILL. With its unmatched precision and cutting-edge technology, RoSS.FILL CGT is a game-changer for the cell and gene therapy industry.

Critical considerations of aseptic single use bag filling

Aseptic bag filling – 5 critical considerations

Aseptic bag filling is a process that is very important to the biopharma industry. This article will give you the basics of aseptic bag filling, highlight the most critical factors of the technique and discuss key considerations pertaining to the commercial use of aseptic bags.

micheal-eder

Michael Eder

Senior Marketing Manager

Michael Eder, MA, is Senior Marketing Manager at Single Use Support. He is expert in pharma and health communication with his 10+ years experience in pharma. After completing his master's degree in International Healthcare Management at MCI The Entrepreneurial school in Innsbruck, he has gained experience in the pharmaceutical field manufacturing and commercialization of OTC and RX drugs. Michael creates articles about Freeze Thaw applications and Platform solutions from Single Use Support and is the author of current news with Single Use Support worldwide. 

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