Fill & Filtration

Explore our insightful articles on fill & filtration processes, offering a wealth of information to enhance your biopharmaceutical operations. Learn about different fill & filtration methods, best practices, and detailed comparisons of solutions from various providers. Our content covers the latest advancements and industry standards, providing valuable insights for applications in viral vector production, mRNA therapies, and fermentation processes. Stay informed with expert analysis and comprehensive guides to optimize your fill & filtration practices.

Featured Articles

Automated aliquoting system: From small volume aliquoting to bulk filling with RoSS.FILL

Fill & Filtration

Aseptic filling & processing of biologics

Many drug products require aseptic conditions along their entire production process. In this article, we will discuss essential considerations on aseptic filling in the biopharma industry.

Michael Eder

January 16, 2024

Fill & Filtration

Fluid management systems: 7 considerations to be made

What are the necessary considerations when implementing automated fluid management systems in biopharma? In this article, we will discuss seven of the most important ones.

Michael Mühlegger

November 13, 2023

Fill & Filtration

Filling of drug substance: 5 threats you should know

When it comes to the filling process of drug substances, there several aspects to be considered to achieve high-quality results with as little product loss as possible. In this article, we will discuss 5 major threats for the filling of drug substances.

Michael Eder

March 20, 2023

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All articles about Fill & Filtration

Single Use Support Dual Sourcing Single Use Assemblies

Fill & Filtration

Dual Sourcing: Strengthening the Pharmaceutical Supply Chain for Single-Use Assemblies

Dual sourcing strategies select suppliers that can meet quality standards, desired delivery times, and overall price expectations. Vendor-agnostic integrators, like Single Use Support, help provide customized single-use systems tailored to specific client needs. This allows them to select the best components and materials from multiple sources, ensuring compatibility and functionality.

David Seifert

October 28, 2024

Fill & Filtration

Aseptic filling machines for pharmaceutical liquids

Aseptic filling machines are widely adopted in the biopharma industry. From individual components and equipment to considerations like scalability – in this article, we will take a closer look at these systems.

Michael Eder

January 16, 2024

Fill & Filtration

Aseptic filling & processing of biologics

Many drug products require aseptic conditions along their entire production process. In this article, we will discuss essential considerations on aseptic filling in the biopharma industry.

Michael Eder

January 16, 2024

Fill & Filtration

Aseptic filling of large volumes of drug substances

Especially in large volume drug manufacturing, aseptic filling can be a challenging yet all the more important task to ensure product safety and effectiveness. In this article, we will discuss what manufacturers ought to be aware of.

Michael Eder

January 16, 2024

RoSS.FILL CGT Lab Scale_product photo (7 von 10)-min

Fill & Filtration

Increasing Patient Safety: Risk assessment for small volume fluid management

Autologous therapies and other ATMPs with small volumes exhibit certain specific requirements. The scope of handling advanced therapies require special handling and care. When handling of small volumes is already automated in an early stage, it is a way more straightforward path to commercialization of the drug product. The benefit of a closed systems with automated solutions add value by offering a higher degree of sterility, safety, and process flexibility.

Brian Moloney

December 4, 2023

Fill & Filtration

Liquid handling in biopharma: Efficiency gains with automated systems

Liquid handling is one of the cornerstones in countless biopharmaceutical manufacturing processes. In this article, we will illustrate how automated systems can improve efficiency – along with several other aspects.

Michael Mühlegger

November 16, 2023

Fill & Filtration

Bioprocess tubing – choosing the right option

Tubing solutions in the field of biopharmaceuticals encompass a wide range of applications, each with its own set of unique challenges and requirements. In this article, we will illustrate them in more detail.

Michael Eder

November 14, 2023

Fill & Filtration

Automated aliquoting system - for small & large volumes

Be it small volume or bulk filling – aliquoting is a necessary step in biopharma manufacturing at every scale. In this article, we will cover the topic of automated aliquoting systems like RoSS.FILL.

Michael Eder

November 14, 2023

Fill & Filtration

Fluid management systems: 7 considerations to be made

What are the necessary considerations when implementing automated fluid management systems in biopharma? In this article, we will discuss seven of the most important ones.

Michael Mühlegger

November 13, 2023

Fill & Filtration

Filling of drug substance: 5 threats you should know

Michael Eder

March 20, 2023

Critical considerations of aseptic single use bag filling

Fill & Filtration

Aseptic bag filling – 5 critical considerations

Aseptic bag filling is a process that is very important to the biopharma industry. This article will give you the basics of aseptic bag filling, highlight the most critical factors of the technique and discuss key considerations pertaining to the commercial use of aseptic bags.

Brian Moloney

March 2, 2022

RoSS.FILL Bag_Product Photo_With Filter_Single Use Support-2 (1)

Fill & Filtration

Bulk filtration for biopharma purposes

In this article we talk about the bulk filtration process in the biopharma industry. We talk about the industries hurdles and why single use components are the future. Learn more why SUSupport has the solution!

Michael Eder

September 22, 2020

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Whitepaper: Automated Aseptic Filling

Read our Whitepaper about Automated Aseptic Filling in Pharmaceutical Manufacturing | Discover why automatic filling solutions are preferable to manual filling.

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Success Story RoSS.FILL: Aseptic Aliquoting in Bioprocessing Applications

A Success Story of the RoSS.FILL Automated Filling Solution that Connects Upstream, Downstream and Fill & Finish. The major technology gaps are filled by automated aseptic dispensing platforms that transfer drug substances from one process step to another, such as from downstream to fill & finish. But the proven record of aseptic filling with RoSS.FILL goes into more areas of application, including seed train intensification, bacterial fermentation, media perparation and fill finish of small volumes in single-use bags.

RoSS.FILL CGT Small Volumne_Product Photo-3-min

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App Note: Enhancing Flexibility & Accuracy With Single Use Support and Sonotec

Enhancing Process Flexibility and Filling Accuracy With Automated Filling. For low volume dispensing at a commercial scale, accuracy and repeatability are essential. To achieve a filling accuracy range of even less than ± 1 mL with the RoSS.FILL platform, Single Use Support decided to implement SONOTEC‘s SONOFLOW CO.55 V3.0 ultrasonic flow meters. Hence, RoSS.FILL users benefit from advanced process safety, flexibility, and scalability with accurate and airless volume dosing.