Drug Delivery

Gain a deep understanding of viral vectors and non-viral vectors and their applications in drug delivery of gene therapies and vaccine development with our informative articles. Single Use Support offers state-of-the-art solutions for the fluid & cold chain management of viral vectors, lipid nanoparticles (LNPs) and more, maintaining their integrity and functionality.

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Drug Delivery

Viral vector manufacturing: Production methods & future advances

Viral vector manufacturing involves advanced biotechnological methods, with scalability being one of the major difficulties. In this article, we will discuss both challenges and innovative approaches for viral vector production.

Khalil Essani

September 20, 2023

Drug Delivery

Non-viral vectors in gene therapy: LNPs in the spotlight

Non-viral vectors play an increasingly important role in biomedical research and therapy, including gene therapy. In this article, we will discuss the role of non-viral vectors for this specific purpose.

Michael Mühlegger

June 13, 2023

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Lentiviral vector manufacturing Single Use Support

Drug Delivery

Lentiviral vector manufacturing: Outdated or advanced gene therapy viruses?

Lentiviral vectors have become important tools in gene therapy, offering new opportunities for treating a wide array of diseases. Learn more about comparison with AAVs and how lentiviral vector manufacturing challenges – from plasmid design to aseptic filling and controlled freezing – can be solved to enhance overall manufacturing efficiency.

Brian Moloney

November 5, 2024

aav-production-efficiency-improvements-single-use-technology

Drug Delivery

AAV production & efficiency improvements with single-use technology

With adeno-associated virus being a popular viral vector, along with a growing interest in gene therapies, there is an increased need for cost-effective vector manufacturing technologies and viral vector production platforms for human gene therapy products.

Khalil Essani

November 19, 2023

Drug Delivery

Challenges in viral vector production & innovative solutions

The challenges in viral vector production are many. The manufacturing process is complex and often demands more flexibility than traditional techniques and devices can offer. Read more!

Brian Moloney

October 21, 2023

Drug Delivery

AAV packaging services: Market overview

Packaging AAVs is crucial as a method to encapsulate a gene of interest within a viral vector. Therefore, we will discuss related methods and services in this article.

Michael Eder

September 21, 2023

ross-kset-single-use-bag-protection-small-bags

Drug Delivery

Viral Vector Vaccine - 7 Facts You Might Not Know

This article will discuss several aspects of viral vector vaccines: We will uncover seven intriguing facts that shed light on this technology: From the ability to mimic infections to the challenges of storage and the diverse applications and more.

Brian Moloney

September 21, 2023

Drug Delivery

Non-viral vectors vs. viral vectors in gene therapy

When designing gene therapies, the choice between non-viral and viral vectors plays an important role in determining the success and safety of therapeutic interventions. Non-viral vectors offer unique advantages, while viral vectors have their own set of strengths and weaknesses. In this blog post, we will explore the types, benefits, and limitations of both non-viral and viral vectors in gene therapy.

Khalil Essani

September 21, 2023

Drug Delivery

Viral vectors in gene therapy – the function, benefits and risks

Gene therapy holds the promise of revolutionizing medical treatments by harnessing the power of viral vectors to deliver therapeutic genes into the genome of patients. In this blog post, we will illustrate these facets of viral vectors in gene therapy in detail.

Khalil Essani

September 21, 2023

Drug Delivery

Viral vector manufacturing: Production methods & future advances

Khalil Essani

September 20, 2023

Drug Delivery

Viral vector vaccines vs. mRNA vaccines: The differences

There are several differences, but also a few significant similarities between viral vector vaccines and non-viral-vector based mRNA vaccines – we will uncover them in this article.

Michael Mühlegger

September 20, 2023

Drug Delivery

Viral vector simply explained

Viral vectors have become an indispensable tools in therapeutic and research applications. In this article, we will provide a broad overview of this fascinating topic.

Michael Mühlegger

September 20, 2023

RoSS.PADL Homogenizing Solution for Aliquot-to-Aliquot consistency

Drug Delivery

Aliquotation & homogenization of viral vectors

In this article, we uncover the significance of a professional aliquotation process, the challenges entailed in filling viral vectors like AAVs, and the innovative solutions supporting to master those challenges.

Brian Moloney

September 20, 2023

Drug Delivery

Freezing & thawing viral vectors: Best practices

Proper handling of viral vectors during storage, freezing, and thawing is crucial to maintaining their integrity and efficacy. In this article, we will explore best practices for preserving viral vectors, ensuring their stability, and maximizing their potential for various applications.

Alexander Fuchs

September 20, 2023

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eBook: Advancing ATMP Fluid Management

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Success Story RoSS.FILL: Aseptic Aliquoting in Bioprocessing Applications

A Success Story of the RoSS.FILL Automated Filling Solution that Connects Upstream, Downstream and Fill & Finish. The major technology gaps are filled by automated aseptic dispensing platforms that transfer drug substances from one process step to another, such as from downstream to fill & finish. But the proven record of aseptic filling with RoSS.FILL goes into more areas of application, including seed train intensification, bacterial fermentation, media perparation and fill finish of small volumes in single-use bags.